Goal-directed intraoperative fluid therapy improved postoperative renal functions in aortic surgical patients
© BioMed Central Ltd. 2007
Published: 22 March 2007
Goal-directed intraoperative fluid therapy reduced the hospital stay after major surgery . Aortic vascular surgery is associated with excessive blood loss and massive fluid shift . We found that postoperative urea and creatinine improved when intravascular fluid volume was maintained using transoesophageal Doppler.
We randomly selected 40 patients who underwent elective infrarenal aortic surgery (aortic aneurysm repair/aortobifemoral grafting). All patients' cardiac output was continuously monitored using a transoesophageal Doppler probe (EDM™; Deltex Medical, Inc., Irving, TX, USA). The corrected flow time (FTc) was recorded immediately after induction as a baseline and recorded again pre-extubation. A target FTc of 375–425 ms was aimed for. The estimated total blood loss was calculated for each patient at the end of surgery. Preoperative and 24-hour postoperative urea and creatinine were recorded for comparison.
Goal-directed intraoperative fluid therapy aiming for FTc of 375–425 ms as a target improved the 24-hour postoperative urea urea and creatinine in 40 aortic surgical patients in spite of the excessive blood loss.
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