Objective
Intact function of the alveolar epithelium is of critical importance to resolve reperfusion edema after lung transplantation. The mechanism, known as alveolar liquid clearance (ALC), can be stimulated by β-adrenergic agents such as terbutaline. ALC in lung grafts and the effect of terbutaline was evaluated in an isolated reperfusion model comparing donor lung injury following brain death in the heart-beating donor (HBD) versus 1 hour of warm ischemia in the nonheart-beating donor (NHBD).