Outcome of patients treated with renal replacement therapy for acute kidney injury

Background

Despite improvement of therapy, mortality remains constant for patients with acute kidney injury (AKI) treated with renal replacement therapy (RRT). The aim was to evaluate the mortality of AKI-RRT patients over a 10-year period.

Methods

A retrospective study on all ICU patients with AKI-RRT in a tertiary-care ICU. Data are presented as the number (interquartile range) or proportion.

Results

Over a 10-year period, 1330 ICU patients had AKI-RRT. Results per year are presented in Table 1. Outcome improved (hazard ratio [HR] [/year] = 0.95 [0.93–0.98], P < 0.001). This trend to improved outcome remained, even after adjustment for age, APACHE II score, vasopressor use or mechanical ventilation at the start of RRT: HR (/year) = 0. 96 [0.94–0.99], P = 0.002).

Table 1

Conclusion

Over a 10-year observation period we observed an improvement in survival for ICU patients with AKI-RRT.