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  • Poster presentation
  • Open Access

Outcome of patients treated with renal replacement therapy for acute kidney injury

  • 1,
  • 1,
  • 1,
  • 1,
  • 1 and
  • 1
Critical Care200610 (Suppl 1) :P296

https://doi.org/10.1186/cc4643

  • Published:

Keywords

  • Public Health
  • Retrospective Study
  • Mechanical Ventilation
  • Replacement Therapy
  • Emergency Medicine

Background

Despite improvement of therapy, mortality remains constant for patients with acute kidney injury (AKI) treated with renal replacement therapy (RRT). The aim was to evaluate the mortality of AKI-RRT patients over a 10-year period.

Methods

A retrospective study on all ICU patients with AKI-RRT in a tertiary-care ICU. Data are presented as the number (interquartile range) or proportion.

Results

Over a 10-year period, 1330 ICU patients had AKI-RRT. Results per year are presented in Table 1. Outcome improved (hazard ratio [HR] [/year] = 0.95 [0.93–0.98], P < 0.001). This trend to improved outcome remained, even after adjustment for age, APACHE II score, vasopressor use or mechanical ventilation at the start of RRT: HR (/year) = 0. 96 [0.94–0.99], P = 0.002).

Table 1

Year

n

Age (years)

APACHE II score (P < 0.01)

Mechanical ventilation (%)

Vasopressors (%)

Dead (%) (P < 0.01)

1995

122

62 (19)

26 (16)

67.2

63.9

72.1

1996

125

63 (17)

24 (12)

66.4

68.0

74.4

1997

126

61 (19)

25 (13)

70.6

73.8

77.0

1998

123

64 (20)

25 (13)

65.9

68.3

65.9

1999

106

66 (17)

26 (12)

56.6

66.0

62.3

2000

101

63 (21)

29 (13)

75.2

69.3

68.3

2001

149

66 (21)

21 (11)

71.8

70.5

57.4

2002

149

63 (22)

29 (10)

67.8

75.2

65.1

2003

173

64 (22)

26 (11)

70.5

76.3

64.7

2004

156

64 (20)

19 (9)

67.3

61.5

52.6

Conclusion

Over a 10-year observation period we observed an improvement in survival for ICU patients with AKI-RRT.

Authors’ Affiliations

(1)
Ghent University Hospital, Gent, Belgium

Copyright

© BioMed Central Ltd 2006

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