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  • Poster presentation
  • Open Access

Osmolar gap as an individual prognostic factor (revised data)

  • 1,
  • 1,
  • 2,
  • 1,
  • 2,
  • 2 and
  • 2
Critical Care200610 (Suppl 1) :P204

https://doi.org/10.1186/cc4551

  • Published:

Keywords

  • Public Health
  • Prognostic Factor
  • Emergency Medicine
  • Cutoff Point
  • Patient Data

Objective

The assessment of the validity of the osmolar gap (OG) as an independent prognostic factor for the mortality of the newly admitted patients compared with the SAPS II and APACHE II scores.

Participants

All the newly admitted patients in two 12 (6 + 6)-bed ICUs regardless of the cause of admission.

Method

Measurement of the freezing point and simultaneous calculation (using the known formula) of plasma osmolarity in every patient at the time of admission. Patient data and the overall outcome at 28 days were documented.

Results

See Table 1. The findings were statistically analysed using a paired t test and a statistically significant difference was obtained (P < 0.001 for SAPS II and OG scores, and P < 0.000 for APACHE II and OG scores, respectively). In addition ROC analysis disclosed for OG an area under the curve of 0.745 ± 0.040 (SE).

Table 1

 

n

SAPS II

APACHE II

Osmolar gap

Survived

90

43.49 ± 15.45

18.22 ± 7.74

11.06 ± 8.83

Died

70

63.68 ± 17.1

26.37 ± 6.14

24.81 ± 24.82

Conclusion

The OG appears to have good correlation with the existing clinical scoring systems and therefore it might be used as an independent prognostic factor. To find out the appropriate cutoff point for the OG obviously requires a greater number of patients in the present study, which is still underway.

Authors’ Affiliations

(1)
General Army Hospital, Athens, 401, Greece
(2)
Athens University Nursing ICU at KAT Hospital, Athens, Greece

Copyright

© BioMed Central Ltd 2006

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