Effects of candiduria-candidemia infections on mortality and morbidity in the ICU and the risk factors of these infections
Published: 21 March 2006
Keywords
Objective
Yeast infections have increasing importance among ICU infections. Candida species have been raised to the fourth most frequently seen ICU infections. Among Candida species, Candida albicans is the most frequently seen yeast infection. We aimed to investigate the candidemia-candiduria ratio, their risk factors, and their mortality and morbidity in ICU patients.
Methods
Intensive care medical records of 935 patients who attended an ICU between 2002 and 2005 were analyzed retrospectively. The risk factors, mortality and morbidity of candiduria-candidemia infections were assessed.
Results
Table 1
Yeast infection | Number of patients | Ratio (%) |
|---|---|---|
Candida infection | 28 | 3 |
Candiduria | 19 | 2 |
Candidemia | 3 | 0.32 |
Candidemia + candiduria | 6 | 0.64 |
Table 2
Risk factor | Candidemia | Candiduria |
|---|---|---|
TPN application (%) | 44.4 | 12 |
Time of mechanical ventilation (days) | 29 | 29 |
Time of ICU stay (days) | 37 | 37 |
APACHE II score | 25 | 20 |
Age (years) | 48.56 | 48.56 |
Use numbers of antibiotics | 2.6 | 2.6 |
Time of antibiotics (days) | 14 | 8.8 |
Days of invasive catheter | 21.4 | 21.4 |
SOFA score | 9.56 | 8.47 |
Conclusion
We found high mortality and morbidity in Candida infections, and there was a relationship between high APACHE II scores, long ICU stay, long mechanical ventilator time, numbers of antibiotics, TPN application, and days of invasive catheter use.
