Table 3 Changes in breathing pattern produced by gradual changes in PEEP
Variable of interest | Changes in PEEP (cmH2O) | ||||
|---|---|---|---|---|---|
from 0 to 5 | from 5 to10 | from 10 to 5 | from 5 to 0 | P | |
Tex (ms) | 229 ± 326 | 260 ± 400 | -271 ± 282 | -218 ± 249 | <0.001 |
rr (breaths/min) | -2.6 ± 4.4 | -1.1 ± 3.5 | 1.3 ± 2.4 | 2.4 ± 4.1 | <0.001 |
VE (l/min) | -0.5 ± 1.9 | -1.2 ± 1.1 | 1.1 ± 1.6 | 0.4 ± 1.3 | <0.001 |
Tin (ms) | 14 ± 73 | -3 ± 54 | 7 ± 57 | -18 ± 61 | NS |
VT (ml BTPS) | 26 ± 93 | -21 ± 40 | 45 ± 97 | -50 ± 41 | NS |
ee-CO2 (%) | 0.0 ± 0.2 | 0.2 ± 0.2 | -0.1 ± 0.2 | -0.1 ± 0.2 | NS |
Vex-CO2 (ml/min) | -27 ± 73 | -82 ± 20 | 67 ± 99 | 42 ± 106 | <0.01 |
V'peak.ex (l/s) | 0.08 ± 0.08 | 0.02 ± 0.09 | 0.00 ± 0.09 | -0.10 ± 0.08 | NS |
VT,ex (ml BTPS) | 18 ± 89 | -18 ± 42 | 49 ± 96 | -50 ± 40 | NS |