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Open Access

Impact of renal scintigraphy in severe patients with acute renal failure

  • JF Ferreira1,
  • JLF Costa1,
  • M Dessen1,
  • AM Mesquita1,
  • MF Garcez1,
  • CT Mesquita1,
  • FL Gutierrez1 and
  • RC Costa-Filho1
Critical Care20059(Suppl 2):P76

Published: 9 June 2005


Acute Renal FailureTechnetiumPlasma Protein BindingChronic DialysisSevere Patient


Acute renal failure (ARF) is frequent in severe patients, producing a poor outcome in the face of its multiple insults that are individually determined [1, 2]. Technetium 99m ethylenedicysteine scintigraphy (Tc-EC) has a very low plasma protein binding and a large volume of distribution. Tc-EC is a good agent for renal function evaluation, providing an index of tubular function and yielding high-quality images [[35]].


To evaluate the clinical impact of renal scintigraphy (RC) in the management of ARF.

Materials and methods

We evaluate all patients in ICUs of a general, private hospital, submitted to RC in the period of January 2003 to January 2004.


Thirty-four patients (18 male), 79.56 ± 16.26 years old, with an APACHE II score of 16.94 ± 6.34 (expected mortality 25%) were studied. The observed mortality was 29.41%. Seventy-three percent of the patients were anuric for 55.36 ± 13.43 days. Dialyses were used in 85.29% of the population and RC always carried through after 30 days. Seventy-four percent of the patients were mechanically ventilated during RC with no transport accident. RC changed the nephrology prescription, interrupted the method or indicated long-term access confection. The radiotracer most used was Tc-EC in 64.70% of the patients. Twenty percent of the patients continued in chronic dialysis and 17.64% had recovered renal function.


RC, mainly with Tc-EC, influenced and modified the clinical impression, nephrological decision, and medical care of severe ARF patients. RC seems to be a good cost-benefit with simple accomplishment method to evaluate glomerular filtration and tubular function with an important impact especially in anuric patients.

Authors’ Affiliations

Núcleo Gestor do Conhecimento em Terapia Intensiva, Hospital Pró-Cardíaco/Nugesco, Rio de Janeiro, Brazil


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© BioMed Central Ltd 2005