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Erratum to: The effect of activated protein C on experimental acute necrotizing pancreatitis

After publication of this work [1] we noticed the following errors:

The surname of the first author was incorrectly written as 'Yamenel' and should be 'Yamanel.'

In the Study Protocol section of the materials and methods, the units for APC dosage should be 'μg/kg' not 'mg/kg.' Please see the corrected section below.

There is a spelling mistake in the fourth paragraph of the discussion. 'Refect' should read 'reflect.'

Study Protocol

After the stabilization period, 45 male rats were randomly divided into three groups. Rats in group I (control group; n = 15) underwent laparotomy with manipulation of the pancreas (sham procedure) and received 10 ml/kg saline intravenously (single dose). Groups II and III underwent laparotomy with induction of ANP. Rats in group II (positive control; n = 15) received saline, as in group I but 6 hours after induction of ANP. Rats in group III (treatment group; n = 15) received 100 μg/kg recombinant human APC (Drotrecogin alfa [activated]; Xigris; Lilly, Istanbul, Turkey) intravenously (single dose) 6 hours after induction of ANP. Twenty-four hours after induction of ANP, all surviving animals were killed by intracardiac infection of pentobarbital (200 mg/kg). Blood samples were taken from the heart before the animals were killed in order to measure serum amylase, TNF-α, and IL-6. Animals that died before the end of the study (four in group II and two in group III) were excluded from the analysis.

References

  1. 1.

    Yamanel L, Mas MR, Comert B, Isik AT, Aydin S, Mas N, Deveci S, Ozyurt M, Tasci I, Unal T: The effect of activated protein C on experimental acute necrotizing pancreatitis. Crit Care. 2005, 9: R184-R190. 10.1186/cc3485.

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Correspondence to Levent Yamanel.

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The online version of the original article can be found at 10.1186/cc3485

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Yamanel, L., Mas, M.R., Comert, B. et al. Erratum to: The effect of activated protein C on experimental acute necrotizing pancreatitis. Crit Care 9, 286 (2005). https://doi.org/10.1186/cc3521

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