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Significant hypophosphatemia following major cardiac surgery: incidence and consequences
Critical Care volume 8, Article number: P266 (2004)
Significant hypophosphayemia (SH) may be associated with respiratory and cardiac complications but has not been targeted as a reversible cause of these complications following cardiac surgery.
Patients and methods
We prospectively studied all patients (n = 566, males 388, females 178, mean age 65.5 [11.1] years) undergoing major cardiac surgery (coronary artery bypass grafting [CABG] 75.4%; aortic valve replacement 5.1%; aortic valve replacement + CABG 5.8%; mitral valve replacement 6.8%; other 6.9%) over a 6-month period. Phosphate levels were measured preoperatively, on admission to the ICU, and on the first postoperative day. Two groups were defined according to the ICU admission level: SH, level <0.48 mmol/l; and a control group, normal range 0.8–1.45 mmol/l. Preoperative, intraoperative and postoperative data were collected in all patients. SH was treated with intravenous sodium or potassium phosphate (0.08 mmol/kg) over 6–12 hours.
Results
Conclusions
As SH after cardiac surgery appears to be common and associated with major morbidity, levels should be routinely monitored.
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Cohen, J., Kogan, A., Sahar, G. et al. Significant hypophosphatemia following major cardiac surgery: incidence and consequences. Crit Care 8 (Suppl 1), P266 (2004). https://doi.org/10.1186/cc2733
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DOI: https://doi.org/10.1186/cc2733