- Poster presentation
- Open Access
Diagnostic value of procalcitonin monitoring in cardiac surgery
© BioMed Central Ltd. 2004
- Published: 15 March 2004
- Infectious Complication
- Postoperative Infectious Complication
- Blood Plasma Sample
- Early Diagnostics
To study the diagnostic value of procalcitonin (PCT) monitoring in adult high-risk patients who underwent valvular surgery.
Sixty high-risk patients (mean age 51 ± 11 years) with two or more risk factors (severe initial condition, proinflammatory diseases in anamnesis, repeated operations, expected cardiopulmonary bypass [CPB] time > 2 hours, age > 60 years, preceding hospitalization and antibacterial therapy) were enrolled into the study. Besides routine clinical investigations, which were performed daily, blood plasma samples were collected before and at 1, 2, 3 and 6 days after surgery. PCT values were determined using the immunoluminometric assay (LUMItest® PCT, BRAHMS Aktiengesellschaft, Germany). All patients were divided into two groups: Group A without and Group B with postoperative infectious complications. All data were compared by t test and P < 0.05 was considered statistically significant.
PCT levels are higher and remain increased for longer in patients with postoperative infection. PCT monitoring is useful for early diagnostics and prediction of severe postoperatice infections in cardiac surgery.