- Meeting abstract
- Open Access
What is the prevalence and clinical relevance of hypocalcemia in sepsis?
© BioMed Central Ltd 2003
- Published: 25 June 2003
- Intensive Care Unit
Hypocalcemia has a prevalence of 88% in general intensive care units (ICUs). Calcium (Ca) administration may be associated with hemodynamic improvement, but with increased mortality in animal studies.
To describe the incidence of hypocalcemia in septic patients, and its associated morbidity and mortality in the first 14 days of ICU stay.
A prospectively collected database was retrieved for Ca and SOFA score at days 1–14, APACHE II, lactate, creatinine, albumin, and mortality. All severe sepsis and septic shock patients were included from June 2000 to June 2001. Patients were classified as presenting severe hypocalcemia (SH) (< 1.0 mmol/l) or moderate hypocalcemia/normocalcemia (> 1.0 mmol/l).
Hypocalcemia is common in septic patients. SH is associated with increased organ dysfunction, and a trend towards increased mortality. It probably represents a sign of more severe disease. More studies are needed to establish the role of calcium supplementation in septic patients.