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Transpulmonary thermodilution technique for cardiac output measurements: single versus double indicator

Introduction

The aim of the study was to compare ITBVI and EVLWI measured by the double indicator (ITBVITD, EVLWITD) [1] with those estimated by the single indicator technique (ITBVIST, EVLWIST) [2].

Methods

Thirty-five patients (24 male, 11 female), mean age 49 (10) years, body surface area 1.8 (0.2) m2, undergoing liver transplantation (Ltx) were studied. Each patient received a pulmonary artery catheter placed via the right internal jugular vein and a 4 Fr thermistor-tipped fiberoptic catheter for thermal dye dilution inserted into the descending aorta connected to the COLD-Z021 (Pulsion Medical System, Munich, Germany). For the double indicator method, a bolus injection was made with cooled (0–4°C) indocyanine green dissolved in glucose 5% in a concentration of 2 mg/ml, and for the single indicator technique 15 ml cooled normal saline was used. Bland and Altman analysis was used for statistical evaluation.

Results

The mean bias between ITBVITD and ITBVIST was 8.6 ml/m2 with a standard deviation of 61.8 ml/m2, and the mean bias between EVLWITD and EVLWIST was -0.2 ml/kg with a standard deviation of 2.2 ml/kg.

Conclusions

The single transpulmonary thermodilution technique is as accurate as the double indicator method for ITBVI and EVLWI estimation.

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References

  1. Sakka SG, et al.: J Crit Care 1999, 14: 78-83. 10.1016/S0883-9441(99)90018-7

    CAS  Article  PubMed  Google Scholar 

  2. Sakka SG, et al.: Intensive Care Med 2000, 26: 180-187. 10.1007/s001340050043

    CAS  Article  PubMed  Google Scholar 

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Costa, M., Pompei, L., Coccia, C. et al. Transpulmonary thermodilution technique for cardiac output measurements: single versus double indicator. Crit Care 7, P192 (2003). https://doi.org/10.1186/cc2081

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  • DOI: https://doi.org/10.1186/cc2081

Keywords

  • Catheter
  • Liver Transplantation
  • Jugular Vein
  • Body Surface Area
  • Bolus Injection