Transpulmonary thermodilution technique for cardiac output measurements: single versus double indicator
© BioMed Central Ltd 2003
Published: 3 March 2003
Thirty-five patients (24 male, 11 female), mean age 49 (10) years, body surface area 1.8 (0.2) m2, undergoing liver transplantation (Ltx) were studied. Each patient received a pulmonary artery catheter placed via the right internal jugular vein and a 4 Fr thermistor-tipped fiberoptic catheter for thermal dye dilution inserted into the descending aorta connected to the COLD-Z021 (Pulsion Medical System, Munich, Germany). For the double indicator method, a bolus injection was made with cooled (0–4°C) indocyanine green dissolved in glucose 5% in a concentration of 2 mg/ml, and for the single indicator technique 15 ml cooled normal saline was used. Bland and Altman analysis was used for statistical evaluation.
The mean bias between ITBVITD and ITBVIST was 8.6 ml/m2 with a standard deviation of 61.8 ml/m2, and the mean bias between EVLWITD and EVLWIST was -0.2 ml/kg with a standard deviation of 2.2 ml/kg.