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Severe acute mitral regurgitation complicating acute myocardial infarction: case for aggressive therapy


The mortality of patients with cardiogenic shock (CS) following acute myocardial infarction (AMI) remains high, despite modern reperfusion strategies. The progressive hemodynamic deterioration in patients with AMI is usually caused by left ventricular systolic dysfunction as a consequence of necrosis or ischaemia. The special subset of CS patients comprises patients with mechanical complications, mainly the severe acute mitral regurgitation (SAMR), ventricular septal and free wall rupture (8%, 6% and 2.7%, respectively, of all CS patients).


Prospective observation of six consecutive patients with SAMR September 2001-October 2002.


See Table 1.

Table 1


Initial aggressive organ support and stabilization followed by mitral valve replacement can offer the patients with SAMR good long-term prognosis.


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Belohlavek, J., Skulec, R., Kovarnik, T. et al. Severe acute mitral regurgitation complicating acute myocardial infarction: case for aggressive therapy. Crit Care 7, P054 (2003).

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  • Mitral Valve
  • Acute Myocardial Infarction
  • Valve Replacement
  • Acute Myocardial Infarction
  • Cardiogenic Shock