- Meeting abstract
- Open Access
Postoperative plasma concentrations of procalcitonin after different types of surgery
© Current Science Ltd 1998
- Published: 1 March 1998
- Plasma Concentration
- Postoperative Period
- Systemic Inflammation
- Postoperative Infection
Procalcitonin (PCT) is an inflammatory induced protein indicating severe bacterial infection or systemic inflammation in critically ill patients. To use PCT for diagnosis of infection or systemic inflammation also in the postoperative period, PCT should not substantially be induced by the surgical trauma in patients with a regular postoperative course. We thus measured PCT and CRP plasma concentrations after different types of surgery in patients with a regular postoperative course.
Postoperative plasma concentrations of PCT and CRP were prospectively measured preoperative and 5 days postoperative in 117 patients with a regular postoperative course and no signs of infection or inflammation after different types of surgery (Table 1).
Postoperative induction of PCT largely depends on the type of surgery. Intestinal surgery and major abdominal operations more often increase PCT, whereas after primarily aseptic surgery PCT is normal in the majority of patients (Table 1). CRP concentrations were increased after all types of surgery (data not shown).
Maximal postoperative PCT plasma concentrations (μg/l) of patients with a regular postoperative course during a 5 day observation period.
Type of surgery
Non-abdominal surgery* (n=37)
Resection of intestine** (n=20)
Major abdom. and retroperitoneal s.*** (n=12)
Cardiac and thoracic surgery (n=37)