Volume 19 Supplement 2

Eighth International Symposium on Intensive Care and Emergency Medicine for Latin America

Open Access

Implication on the prognosis according to the cause of heart failure decompensation

  • Pedro Gabriel MB Silva1,
  • Flavio Brito1,
  • Mariana Okada1,
  • Patricia Roveri1,
  • Douglas Ribeiro1,
  • Giuliano Generoso1,
  • Jose Teixeira1,
  • Thiago Macedo1,
  • Antonio Baruzzi1 and
  • Valter Furlan1
Critical Care201519(Suppl 2):P9

https://doi.org/10.1186/cc14665

Published: 28 September 2015

Introduction

Heart failure (HF) is responsible for the majority of hospitalizations due to cardiovascular disease, and different clinical triggers are related to the cardiac decompensation.

Objective

To evaluate the prognosis of patients hospitalized due to acute HF, according to the cause of decompensation.

Methods

We retrospectively evaluated data from 731 patients consecutively admitted to a private cardiovascular center due to acute HF during 2013. We analyzed the frequency of each factor assigned as the trigger for the decompensation of HF among these patients, and also the length of stay and the number of deaths in each group. The infection group was compared with the other two groups separately, using Fisher's exact test for categorical variables and Student's t test for continuous variables.

Results

The factor "infection" was associated with more days of hospitalization (Table 1), above the average of other triggers (10 × 6.95 days; p <0.01). The number of days in ICU in the cases of decompensation due to infection was also higher than the average from other causes (5.8 × 3.35 days; p <0.01). In addition, of the 48 deaths in 2013, 58% (n = 28) were in patients with decompensated HF due to infection, and among these 28 deaths 15 were secondary to evolution of sepsis, in 6 there were predominance of the cardiac condition while the remaining 7 deaths showed mixed shock (cardiac and septic) or other complications related to both conditions leading to death. Conclusion: Infection was the main factor of decompensation, requiring a longer hospital stays, more days in the ICU and being responsible for most of the deaths occurred in patients hospitalized for acute HF. Studies of specific approaches in acute HF triggered by infection are warranted.

Table 1

 

Infection (n= 253)

Noncompliance (n= 126)

Progress of disease (n= 191)

pvalue

ICU stay (days)

5.8 (± 9)

3.7 (± 3.9)

3.2 (± 3.1)

0.013 and <0.001

Length of stay (days)

10 (±9.2)

7 (± 5.7)

8.1 (± 7.3)

0.019 and <0.001

In-hospital mortality (%)

11.1

3

5.2

0.009 and 0.039

Readmission in 30 days (%)

21.3

19.8 %

12

0.78 and 0.011

Conclusion

Infection was the main factor of decompensation, requiring a longer hospital stay, more days in the ICU and being responsible for most of the deaths occurring in patients hospitalized for acute HF. Studies of specific approaches in acute HF triggered by infection are warranted.

Authors’ Affiliations

(1)
Hospital Totalcor, Cerqueira Cesar, São Paulo

Copyright

© M.B. Silva et al.; 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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