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Volume 19 Supplement 1

35th International Symposium on Intensive Care and Emergency Medicine

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Coagulation support algorithm with rapid TEG and functional fibrinogen TEG in critical bleeding: more results and less time

Critical Care volume 19, Article number: P352 (2015) Cite this article

Introduction

Early coagulation support is essential in massively bleeding patients. A Coagulation Support Algorithm (CSA), integrating rapid TEG (r-TEG) and functional fibrinogen TEG (ff-TEG) could shorten the time to a tailored treatment (Figure 1).

Figure 1
figure 1

Coagulation Support Algorithm.

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Methods

A retrospective comparison of the time to available TEG and Standard Coagulation Tests (SCT: INR, aPTTr, fibrinogen level) results in two groups of bleeding and coagulopathic patients using citrate kaolin-TEG (k-TEG) or the CSA protocol (r-TEG/ff-TEG). Statistical analysis was performed with Student's t test for unpaired samples.

Results

Twenty-three patients for each k-TEG and CSA group were compared. The time to available results was shorter using the CSA protocol in comparison with k-TEG (Table 1). The differences were both statistically (P < 0.00001) and clinically (mean reduction time 21 minutes) significant. SCT needed the longest time to obtain the final results.

Table 1 Comparison of time to results.
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Conclusion

The implementation of a CSA, including r-TEG and ff-TEG, could shorten the time to a targeted treatment in critically bleeding patients.

References

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Authors and Affiliations

  1. Hospital G. Rummo, Benevento, Italy

    E De Blasio, C Pellegrini, A Federico, V Rocco, M Fumi, Y Pancione, S Sale & D Liberti

Authors
  1. E De Blasio
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  2. C Pellegrini
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  3. A Federico
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  4. V Rocco
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  5. M Fumi
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  6. Y Pancione
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  7. S Sale
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  8. D Liberti
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Blasio, E.D., Pellegrini, C., Federico, A. et al. Coagulation support algorithm with rapid TEG and functional fibrinogen TEG in critical bleeding: more results and less time. Crit Care 19 (Suppl 1), P352 (2015). https://doi.org/10.1186/cc14432

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  • DOI: https://doi.org/10.1186/cc14432

Keywords

Critical Care

ISSN: 1364-8535