Volume 5 Supplement 4
'Alveolar recruitment strategy' improves arterial oxygenation after cardiopulmonary bypass
© BioMed Central Ltd 2001
Published: 7 November 2001
Atelectasis occurs during general anaesthesia . During cardiopulmonary bypass, this atelectasis is exacerbated by the physical collapse of the lungs. As a result, poor arterial oxygenation is often seen post-operatively. Studies using an alveolar recruitment strategy have improved oxygenation after non-cardiac surgery .
We tested the effect of an 'alveolar recruitment strategy' on arterial oxygenation in a prospective, randomised, controlled study of 78 patients undergoing cardiopulmonary bypass. Divided equally into three groups of 26, Group 'No PEEP' received standard post bypass manual lung inflation, and no PEEP applied until on ICU. Group '5 PEEP' received standard post bypass manual inflation, and then 5 cmH2O PEEP applied and maintained until extubation on ICU. The third group 'treatment group', received a pressure controlled stepwise increase in PEEP up to 15 cmH2O and tidal volumes of 18 ml/kg or a peak inspiratory pressure of 40 cmH2O was reached. This was maintained for 10 cycles, and the PEEP of 5 cmH2O was maintained until extubation on ICU. Arterial blood samples were analysed at 30 min post induction of anaesthesia, and then at 30 min, 1, 2 and 6 hours post bypass. The length of ICU stay, hospital stay and incidence of chest infections was recorded.
We conclude that the application of an alveolar recruitment strategy improves arterial oxygenation up to one hour after cardiopulmonary bypass surgery. We hypothesize that this improvement is lost after one hour due to routine ICU nursing care which includes open circuit suctioning and disconnections from the ventilator thus removing the PEEP. This would allow atelectasis to reoccur. The results of this study suggest that the early impairment of gas exchange that occurs postoperatively in cardiac surgery can be reversed, thus allowing for earlier extubation.
- Lindberg P, Gunnarson L, Tokics L, Secher E, Lundquist H, Brismar B, Hedenstierna G: Atelectasis and lung function in the postoperative period. Acta Anaesthesiol Scand 1992, 36: 546-553.View ArticlePubMedGoogle Scholar
- Tusman G, Bohm SH, Vasquez de Anda GF, do Campo JL, Lachmann B: 'Alveolar recruitment strategy' improves arterial oxygenation during general anaesthesia. Br J Anaesth 1999, 82: 8-13.View ArticlePubMedGoogle Scholar