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Assessment of specific risk scores for patients admitted to the ICU for severe community-acquired pneumonia
Critical Care volume 19, Article number: P9 (2015)
The aim of the study is to evaluate the calibration and discrimination of two specific risk scores for community-acquired pneumonia (CAP) in patients with this illness who required ICU admission.
A retrospective descriptive study of patients with severe CAP admitted to the ICU between January 2008 and September 2013. We analyzed clinical and epidemiological variables and APACHE II, SAPS III, CURB-65 and Pneumonia Severity Index (PSI) that were recorded in the first 24 hours. We used the Student t test to compare means and the chi-square test for univariate analysis. The standardized mortality ratio (SMR) and Hosmer-Lemershow test were calculated to analyze the calibration and ROC curve analysis for discrimination of different scores.
We analyzed 111 patients aged 57.5 ± 17.7 years, with 63.1% (70) males. The APACHE II score at admission was 19.8 ± 17.7 and SAPS III was 60.6 ± 16.7. ICU mortality was 29.7% (33). There was association between the four scores and mortality. The SMR for APACHE II was 0.87 and 0.85 for the SAPS III. Figure 1 shows the ROC curve for the four scores, the best observed discrimination obtained was for SAPS III score (AuC 0.79) and the worst was obtained for CURB-65 score (AuC 0.7). The Hosmer-Lemeshow test showed acceptable calibration for the four predictive systems (P > 0.05).
The four analyzed scores presented good calibration, but discrimination seems better in SAPS III. Given the difficulty of calculating PSI, and its low discrimination (similar to CURB-65), we prefer to use the CURB-65 score in routine clinical practice.
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Joya-Montosa, C., Delgado-Amaya, M., Trujillo-García, E. et al. Assessment of specific risk scores for patients admitted to the ICU for severe community-acquired pneumonia. Crit Care 19, P9 (2015). https://doi.org/10.1186/cc14089
- Standardize Mortality Ratio
- Pneumonia Severity Index
- Epidemiological Variable
- Retrospective Descriptive Study
- Acceptable Calibration