A 10-second fluid challenge guided by transthoracic echocardiography can predict fluid responsiveness

Table 3 Accuracy of echocardiographic parameters for predicting fluid responsiveness

	AUC	Cutoff values	Sensitivity	Specificity	Positive predictive value	Negative predictive value
∆VTI50	0.91 ± 0.04	9%	74%	95%	94%	79%
∆VTI500	0.95 ± 0.03	19%	89%	100%	100%	90%
∆CO50	0.95 ± 0.03	6%	93%	91%	91%	93%
∆SV50	0.96 ± 0.03	10%	90%	100%	100%	91%
∆SV500	1.00	15%	100%	100%	100%	100%

∆CO50, variation of cardiac output after infusion of 50 ml of fluid over 10 seconds; ∆SV50, variation of stroke volume after infusion of 50 ml of fluid over 10 seconds; ∆SV500, variation of stroke volume after infusion of 500 ml fluid over 15 minutes; ∆VTI50, variation of velocity time index after infusion of 50 ml of fluid over 10 seconds; ∆VTI500, variation of velocity time index after infusion of 500 ml of fluid over 15 minutes; AUC, area under the receiver operating characteristic curves.

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