Predicting 6-month mortality of patients with traumatic brain injury: usefulness of common severity scores
© Skrifvars et al.; licensee BioMed Central Ltd. 2014
Published: 17 March 2014
Severity of illness scoring systems is paramount for the evaluation of quality of care of critically ill and trauma patients [1–3]. The purpose of the present study was to evaluate the usefulness of the Acute Physiology and Chronic Health Evaluation II (APACHE II), Simplified Acute Physiology Score II (SAPS II) and Sequential Organ Failure Assessment (SOFA) scores in predicting long-term outcome of patients with moderate-to-severe traumatic brain injury (TBI).
A Finnish multicenter ICU database was screened for TBI patients admitted in 2003 to 2012. Logistic regression was used for customization of the APACHE II, SAPS II and SOFA for 6-month mortality prediction. An adjusted SOFA model, including age, and a reference model, including only age and Glasgow Coma Scale, were built for comparison. A randomized split-sample technique was used for internal validation and prognostic performance was determined by assessing discrimination, calibration and precision.
A simple prognostic model, based only on age and GCS, displayed a fairly good prognostic performance in predicting 6-month mortality of ICU-treated patients with moderate-to-severe TBI. The use of more complex scoring systems added little to the prognostic performance.
- Rothen , et al.: Curr Opin Crit Care. 2008, 14: 513-519. 10.1097/MCC.0b013e32830864e9View ArticlePubMedGoogle Scholar
- Woodhouse , et al.: Curr Opin Crit Care. 2009, 15: 450-455. 10.1097/MCC.0b013e32833079fbView ArticlePubMedGoogle Scholar
- Ridley , et al.: Anaesthesia. 1998, 53: 1185-1194. 10.1046/j.1365-2044.1998.00615.xView ArticlePubMedGoogle Scholar
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