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Glycaemia and critical care outcomes
Critical Care volume 18, Article number: P441 (2014)
The aim of this study was to determine the impact of preadmission or first 24-hour blood glucose (BG) measurements in UK ICUs on mortality.
The Intensive Care National Audit & Research Centre case-mix programme database on adult admissions to general, neuroscience and cardiothoracic critical care units was used for analysis. Within the database, the highest and lowest blood glucose (BG) values measured during the first 24 hours from admission were recorded. BG control value was defined as BG (≥4.0 ≤9.9 mmol/l). Other BG levels were defined as: very low, ≤2.2 mmol/l (≤40 mg/dl); low, >2.2 ≤3.9 mmol/l (40 to 70 mg/dl); high, ≥10.0 <11.1 mmol/l (180 to 200 mg/dl); and very high, ≥11.1 mmol/l (200 mg/dl).
There was an increased incidence of mortality in those patients with at least one BG measure below 3.9 mmol/l (70 mg/dl) compared with those without (Table 1). There was a link between BG levels and LoS for surviving patients with the longest hospital stays (critical care and total hospital) experienced by those with BG levels below 2.2 mmol/l (40 mg/dl).
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The NICE-SUGAR Study Investigators: Intensive versus conventional glucose control in critically ill patients N Engl J Med 2009, 360: 1283-1297.
Funding from Edwards Lifesciences.
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Cecconi, M., Ryan, C., Dawson, D. et al. Glycaemia and critical care outcomes. Crit Care 18 (Suppl 1), P441 (2014). https://doi.org/10.1186/cc13631
- Blood Glucose
- Blood Glucose Level
- Critical Care
- Blood Glucose Control
- Longe Hospital Stay