Skip to main content
  • Poster presentation
  • Published:

High-frequency oscillatory ventilation use in patients with H1N1: a single-centre review


Limited evidence exists as to the value of high-frequency oscillatory ventilation (HFOV) for patients with H1N1 [1][2]. We describe a subgroup of patients, from a single UK centre, who received HFOV and had H1N1-positive virology.


Local permissions for research were obtained. Patients with confirmed H1N1 who underwent HFOV between 2008 and 2012 were included. Data collected retrospectively included demographics, diagnosis, illness severity and outcome measures.


We identified 10 patients (Table 1) who received both HFOV and had confirmed H1N1. Two patients were transferred to a tertiary centre to receive ECMO and both critical care and 6-month mortality were 40%.

Table 1 Patient characteristics


This study adds to the literature on the use of HFOV in H1N1 patients. We managed to replicate some of the existing evidence in respect to the population age [1][2] and the incidence of mortality. Whilst P/F ratios improved on initiation of HFOV, these patients subsequently had long critical care and hospital stays. There is uncertainty regarding the use of HFOV in ARDS, but it may be a valuable treatment for H1N1 patients. The ventilation strategies employed and the subsequent consequences for H1N1 patients require further evaluation.


  1. Riscilli BP, et al.: PLOS One. 2011. doi: 10.1371/journal.pone.0018166

    Google Scholar 

  2. Boots RJ, et al.: Anaesth Intensive Care. 2011, 39: 837-846.

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations


Rights and permissions

Reprints and permissions

About this article

Cite this article

Smith, N., Pathmanthan, N., Martinson, V. et al. High-frequency oscillatory ventilation use in patients with H1N1: a single-centre review. Crit Care 18 (Suppl 1), P290 (2014).

Download citation

  • Published:

  • DOI: