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Table 1 Arterial blood gas parameters and end-tidal CO 2 (P ET CO 2 )

From: Lipopolysaccharide infusion enhances dynamic cerebral autoregulation without affecting cerebral oxygen vasoreactivity in healthy volunteers

 

Baseline

LPS

 

Normoxia

Hyperoxia

Hypoxia

Normoxia

Hyperoxia

Hypoxia

PaO2 (kPa)

13.2

28.5**

7.5**

11.6†

26.7**

7.1**

(12.8–14.3)

(27.4–29.1)

(6.0–8.2)

(11.0–13.1)

(26.4–27.0)

(6.6–7.3)

SaO2 (%)

98

100**

90**

98

100**

89**

(98–99)

(100–100)

(82–92)

(98–98)

(100–100)

(85–91)

CaO2 (mM)

8.4

8.7*

7.5**

8.3

8.7**

7.4**

(8.1–8.9)

(8.6–9.0)

(7.2–7.8)

(8.0–8.8)

(8.3–9.1)

(7.1–8.3)

PaCO2 (kPa)

5.7

5.6

5.7

5.0††

5.0††

4.8††

(5.6–5.8)

(5.2–6.0)

(5.5–5.8)

(5.0–5.1)

(4.8–5.0)

(4.7–5.1)

pH (units)

7.39

7.40

7.41*

7.43†

7.43

7.45*††

(7.38–7.41)

(7.40–7.42)

(7.39–7.42)

(7.42–7.44)

(7.41–7.45)

(7.42–7.47)

HCO3- (mM)

25.0

25.1

25.0

25.3

25.9

25.5

(24.4–26.6)

(23.9–26.4)

(24.5–26.2)

(24.8–26.0)

(24.7–26.7)

(24.2–26.0)

Base excess (mM)

0.9

1.0

1.6

1

1

0.9†

(0.2–2.7)

([-0.4]–2.4)

(0.7–2.7)

(0.2–2.3)

(0.1–2.1)

(0–2.4)

PETCO2 (kPa)

5.4

5.2

5.2

5.3

5.2

5.1*

 

(5.1–5.4)

(5.2–5.4)

(5.1–5.3)

(5.2–5.4)

(5.1–5.3)

(5.1–5.2)

  1. A blood sample was obtained from the radial artery catheter during three interventions, normoxia (FIO2 = 21 %), hyperoxia (FIO2 = 40%) and hypoxia (FIO2 = 12%), at baseline, and after a four-hour lipopolysaccharide (LPS) infusion in healthy volunteers (n = 10). CaO2: arterial oxygen content. Data are presented as median (interquartile range). Different from normoxia in the same condition (baseline/LPS), *P<0.05, **P<0.01. Different from the same intervention (normoxia/hyperoxia/hypoxia) at baseline, †P<0.01, ††P<0.001.
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