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Volume 17 Supplement 4

Sepsis 2013

Open Access

Elapsed time between ICU request and actual admission of patients with SIRS/sepsis leads to an increase in mortality or length of stay in this unit?

  • Edmilson Bastos de Moura1,
  • Fábio Ferreira Amorim2,
  • Adriell Ramalho Santana2,
  • Jaqueline Lima de Souza2,
  • Felipe Bozi Soares2,
  • Bárbara Magalhães Menezes2,
  • Mariana Pinheiro Barbosa de Araújo2,
  • Fernanda Vilas Bôas Bôas Araújo2,
  • Louise Cristhine de Carvalho Santos2,
  • Pedro Henrique Gomes Rocha2,
  • Guilherme Menezes de Andrade Filho2,
  • Thiago Alves Silva2,
  • Pedro Nery Ferreira Júnior2,
  • Alethea Patrícia Pontes Amorim3,
  • José Aires de Araújo Neto1 and
  • Marcelo de Oliveira Maia1
Critical Care201317(Suppl 4):P56

Published: 5 November 2013


Relative RiskHigh MortalitySeptic ShockEmergency MedicineEarly Treatment


Measures to ensure an appropriate early treatment for critically ill patients result in significant decreases in mortality [1, 2]. This study aims to evaluate the impact of the elapsed time between ICU request and actual admission of patients with SIRS/sepsis on ICU mortality and length of stay.

Materials and methods

Retrospective cohort study conducted in the ICU of Hospital Santa Luzia, Brasilia, DF, during 3 months. Patients being consecutively admitted to the ICU with diagnostic of SIRS/sepsis were divided into two groups: those with elapsed time between ICU request and admission less than 6 hours (short waiting period group (SWP)) or over 6 hours (long waiting period group (LWP)).


A total of 70 patients were enrolled (46% of admissions), 14 patients with SIRS, 27 with sepsis, 13 with severe sepsis and 17 with septic shock. For the entire cohort, the mean age was 61 ± 22 years, APACHE II was 12 ± 7.7, ICU length of stay was 15 ± 22.8 days, and 39 were male (54,9%). Thirty-five patients belonged to the LWP (50%). LWP patients had higher mortality (50% vs. 19.6%, P = 0.04), and longer ICU length of stay (13.6 ± 18.5 vs. 23.5 ± 40.7 days, P = 0.04). Relative risk for death in the LWP was 2.83 (95% CI: 1.28 to 6.28).


The elapsed time between ICU request and actual admission of patients with SIRS/sepsis over 6 hours resulted in increased ICU mortality and ICU length of stay for this group of patients.

Authors’ Affiliations

Hospital Santa Luzia, Brasília, Brazil
Escola Superior de Ciências da Saúde, Brasília, Brazil
Liga Acadêmica de Medicina Intensiva de Brasília, Brazil


  1. Amorim FF, Santana AR, Biondi RS, Amorim AP, Moura EB, Quadros KJ, Oliveira HS, Ribeiro RA: Difference in patient outcomes coming from public and private hospitals in an intensive care unit in Brazil. J Clin Med Res. 2012, 4: 410-414.PubMed CentralPubMedGoogle Scholar
  2. Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, Peterson E, Tomlanovich M: Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med. 2001, 345: 1368-1377. 10.1056/NEJMoa010307.View ArticlePubMedGoogle Scholar


© de Moura et al.; licensee BioMed Central Ltd. 2013

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.