Organ dysfunction and mortality in septic patients admitted to an ICU
- Thais Almeida Rodrigues1,
- Louise Cristhine de Carvalho Santos1,
- Jaqueline Lima de Souza1,
- Fernanda Vilas Bôas Araújo1,
- Thiago Alves Silva1,
- Pedro Henrique Gomes Rocha1,
- Lucila de Jesus Almeida1,
- Jacqueline Rodrigues de Carvalho1,
- Mariana Pinheiro Barbosa de Araújo1,
- Lucas Garcia de Souza Godoy1,
- Kátia Crys Moura Ogliari1,
- Pedro Nery Ferreira Júnior1,
- Adriell Ramalho Santana2,
- Fábio Ferreira Amorim1 and
- Clayton Barbieri de Carvalho3
© Rodrigues et al.; licensee BioMed Central Ltd. 2013
Published: 5 November 2013
Sequential Organ Failure Assessment (SOFA) is a largely used score in the evaluation of organ dysfunction/failure in septic patients . Repeated scoring can also assess patient condition and disease development . The present study aims to describe the association between SOFA score and the organ dysfunction components of this score with mortality in septic patients admitted to an ICU.
Materials and methods
Prospective study conducted on patients admitted to the ICU of Hospital Regional de Samambaia, Brasília, DF, Brazil, during 7 months. The SOFA was evaluated at the time of admission to the ICU. Patients were divided into two groups: survivors group (SG) and nonsurvivors group (NSG). Accuracy of SOFA and the organ dysfunction components of SOFA score to predict ICU mortality were measured with the area under the receiver operating characteristic (ROC) curve.
The SOFA score was moderately associated with ICU mortality. The scores for cardiovascular and renal impairment were individually associated with mortality.
- Vincent JL, de Mendonça A, Cantraine F, Moreno R, Takala J, Suter PM, Sprung CL, Colardyn F, Blecher S: Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: results of a multicenter, prospective study. Working group on 'sepsis-related problems' of the European Society of Intensive Care Medicine. Crit Care Med. 1998, 26: 1793-1800. 10.1097/00003246-199811000-00016.View ArticlePubMedGoogle Scholar
- Vincent JL, Moreno R, Takala J, Willatts S, De Mendonça A, Bruining H, Reinhart CK, Suter PM, Thijs LG: The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. Intensive Care Med. 1996, 22: 707-710. 10.1007/BF01709751.View ArticlePubMedGoogle Scholar
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.