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Volume 17 Supplement 4

Sepsis 2013

Open Access

Comparison of demographics and outcomes of patients with severe sepsis admitted to the ICU with or without septic shock

  • Bárbara Magalhães Menezes1,
  • Fernanda Vilas Bôas Araújo1,
  • Fábio Ferreira Amorim1,
  • Adriell Ramalho Santana1,
  • Felipe Bozi Soares1,
  • Jacqueline Lima de Souza1,
  • Mariana Pinheiro Barbosa de Araújo1,
  • Louise Cristhine de Carvalho Santos1,
  • Pedro Henrique Gomes Rocha1,
  • Mateus Gonçalves Gomes1,
  • Osvaldo Gonçalves da Silva Neto1,
  • Pedro Nery Ferreira Júnior1,
  • Alethea Patrícia Pontes Amorim2,
  • Rodrigo Santos Biondi3 and
  • Rubens Antônio Bento Ribeiro3
Critical Care201317(Suppl 4):P48

https://doi.org/10.1186/cc12948

Published: 5 November 2013

Keywords

Public HealthMortality RateHigh MortalitySeptic ShockEmergency Medicine

Background

Severe sepsis and septic shock are common and are associated with substantial mortality and substantial consumption of healthcare resources [1]. Although the incidence of septic shock has steadily increased during the past several decades, the associated mortality rates have remained constant or have decreased only slightly [2]. This study aims to compare demographics and outcomes of patients admitted to the ICU with severe sepsis and with or without septic shock.

Materials and methods

The present study is a retrospective cohort conducted over a 3-year period in the ICU of Hospital Anchieta, Brasília, Brazil. Patients were divided into two groups: severe sepsis without shock septic (SW) and severe sepsis with septic shock (SS). The patients coming from other ICUs or transferred to other ICUs were excluded.

Results

A total of 198 patients with severe sepsis were enrolled in this study. Among them, 97 patients (49%) had septic shock. In this cohort, the mean age was 59 ± 16 years, the SAPS 3 score was 63 ± 17 and the APACHE II score was 21 ± 9. The mortality in four days was 12.6% (n = 25), in 28 days was 14.1% (n = 28) and the hospital mortality was 29.3% (n = 58). There was no difference between the two groups regarding age (64 ± 20 vs. 59 ± 21, P = 0.08) and length of stay in the ICU (12 ± 1 vs. 11 ± 1, P = 0.51). The SS group presented higher SAPS3 (70 ± 17 vs. 57 ± 15, P = 0.00) and APACHE II (1 vs. 8 ± 9 ± 1, P = 0.00) scores. Patients in the SS group also had higher mortality in 4 days (18% vs. 8%, P = 0.04), in 28 days (20% vs. 9%, P = 0.03) and hospital mortality (37% vs. 22%, P = 0.02).

Conclusions

Patients admitted with septic shock had higher mortality than patients admitted with severe sepsis without septic shock, but there was no difference between the groups with respect to length of stay in the ICU.

Authors’ Affiliations

(1)
Escola Superior de Ciências da Saúde, Brasília, Brazil
(2)
Liga Acadêmica de Medicina Intensiva de Brasília, Brazil
(3)
Hospital Anchieta, Brasília, Brazil

References

  1. Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, Peterson E, Tomlanovich M: Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med. 2001, 345: 1368-1377. 10.1056/NEJMoa010307.View ArticlePubMedGoogle Scholar
  2. Gauer RL: Early recognition and management of sepsis in adults: the first six hours. Am Fam Phys. 2013, 88: 44-53.Google Scholar

Copyright

© Menezes et al.; licensee BioMed Central Ltd. 2013

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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