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ICU acquired acute renal failure carries a higher mortality than acute renal failure on admission to ICU
Critical Care volume 5, Article number: P222 (2001)
Acute renal failure (ARF) has a significant impact on outcome of critically ill patients [1]. The aim of this study was to identify any differences between patients with ARF on admission to the intensive care unit (ICU) and patients developing ARF during their stay in the ICU. We retrospectively analysed data from The Riyadh Intensive Care Program (RIP) database which contains demographic data of 26,669 patients admitted to 21 ICUs in the United Kingdom (UK) during the time period June 1989 until September 1996. ARF was defined according to the organ system failure scoring system by Knaus et al [2]. Patients with chronic renal failure were excluded.
Comment
Our study confirms that ARF increases mortality in ICU patients with a further marked increase amongst patients who require renal replacement therapy (RRT). Patients who develop ARF during their stay in the ICU have a significantly worse outcome compared to patients with ARF on admission to ICU.
References
Levy EM, Viscoli CM, Horwitz RI: The effect of acute renal failure on mortality - a cohort analysis. JAMA 1996, 275: 1489-1494. 10.1001/jama.275.19.1489
Knaus WA, Draper EA, Wagner DP, Zimmermann JE: Prognosis in acute organ-system failure. Am Surg 1985, 202: 685-693.
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Ostermann, M., Nelson, S. & Chang, R. ICU acquired acute renal failure carries a higher mortality than acute renal failure on admission to ICU. Crit Care 5 (Suppl 1), P222 (2001). https://doi.org/10.1186/cc1289
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DOI: https://doi.org/10.1186/cc1289
Keywords
- Public Health
- Intensive Care Unit
- Renal Failure
- High Mortality
- Replacement Therapy