Figure 2
From: Effects of ventilation strategy on distribution of lung inflammatory cell activity
Regional gas, perfusion and shunt fractions. Gas fraction (fgas) (A), perfusion fraction (B) and shunt fraction (C) for isogravitational (dependent, middle and nondependent) regions of interest of injurious (open symbols) and protective ventilation (filled symbols) groups at baseline (triangles) and after (circles) 2 h of mechanical ventilation and endotoxemia (ETX). fgas and perfusion fraction were stable over time in both groups. In contrast, shunt fraction dramatically increased over time in dependent regions of the injurious ventilation group, but not in those of the protective ventilation group. Horizontal lines represent median values. *P < 0.05, **P < 0.01 and ***P < 0.001. P values are derived from two-way analysis of variance with repeated measurements and Bonferroni adjustments for multiple comparisons.