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Association of sleep disordered breathing with clinical trajectories in patients undergoing cardiac surgery
Critical Care volume 17, Article number: P495 (2013)
Polygraphic recordings of 181 patients, without previous diagnosis of SDB, undergoing standard cardiac surgical procedures with extracorporeal circulation were obtained during a preoperative night. The apnea-hypopnea index (AHI - the number of apneas, hypopneas per hour recorded) was determined and compared with clinical characteristics and postoperative course.
The prevalence of SDB was considerably high among all examined patients. Median AHI was 20.8 (interquartile range, 10.6 to 36.4). Preoperative AHI was >30 in 32% of all examined individuals. During the first three postoperative days, preoperative AHI >30 was associated with a prolonged weaning time, a reduced oxygenation index (arterial pO2/FiO2), an impaired kidney function, an augmented inflammatory response and an overall increased length of stay in the ICU. The observed association of high preoperative AHI values with postoperative clinical characteristics remained statistically significant throughout the first three postoperative days.
Undiagnosed SDB is highly prevalent among cardiac surgical patients. Clinical trajectories of individuals with severe SDB are described by a prolonged recovery of pulmonary function, delayed weaning and a pronounced inflammatory response after surgery. Screening for SDB might identify patients that are susceptible for a complicated postoperative course.
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Roggenbach, J., Tan, B., Von der Leyen, E. et al. Association of sleep disordered breathing with clinical trajectories in patients undergoing cardiac surgery. Crit Care 17, P495 (2013). https://doi.org/10.1186/cc12433
- Sleep Disorder
- Sleep Disorder Breathing
- Oxygenation Index
- Extracorporeal Circulation
- Relevant Impact