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Table 3 Unadjusted associations between clinical factors and psycho-social outcomes three months after intensive care

From: Investigating risk factors for psychological morbidity three months after intensive care: a prospective cohort study

 

Post-traumatic stress disorder*

Depression

Anxiety

Mental

quality of life

Physical

quality of life

TISS (Therapeutic intervention scoring)

0.25

. P = 0.01

0.08

P = 0.44

0.07

P = 0.52

-0.06

P = 0.62

0.04

P = 0.74

Number of organs supported

0.26

P <0.01

0.12

P = 0.23

0.06

P = 0.57

-0.08

P = 0.47

0.08

P = 0.49

Duration of sedation

0.27

P <0.01

0.19

P = 0.07

0.17

P = 0.09

-0.20

P = 0.06

0.03

P = 0.82

Number of drug groups

0.28

P <0.01

0.10

P = 0.32

0.10

P = 0.31

-0.10

P = 0.47

-0.20

P = 0.07

Length of stay in ICU

0.11

P = 0.29

-0.05

P = 0.66

-0.06

P = 0.58

-0.02

P = 0.87

0.02

P = 0.87

Length of hospital stay

0.15

P = 0.15

0.21

P <0.05

0.09

P = 0.39

-0.18

P = 0.12

-0.07

P = 0.56

Type of admission†

P = 0.81

P = 0.50

P = 0.23

P = 0.81

P = 0.53

Post-hospital destination

P = 0.38

P <0.05

P = 0.25

P = 0.22

P = 0.90

Primary body system

P = 0.20

P = 0.03

P = 0.14

P = 0.30

P = 0.17

Duration of mechanical ventilation

0.20

P <0.05

0.09

P = 0.39

0.06

P = 0.57

-0.013

P = 0.91

-0.014

P = 0.90

Duration of cardiovascular support

0.25

P <0.05

0.14

P = 0.17

0.13

P = 0.22

-0.20

P = 0.06

-0.03

P = 0.79

Benzodiazepines ‡

6.96 (2.36, 11.57)

P <0.01

7.44 (1.81, 13.07)

P = 0.01

5.95 (0.03, 11.87)

P <0.05

-4.08 (-8.73, .56)

P = 0.08

-.27 (-4.67, 4.12)

P = 0.90

Anaesthestics

1.64 (-3.35, 6.65)

P = 0.51

-2.35 (-8.50, 3.80)

P = 0.45

-2.61 (-8.88, 3.65)

P = 0.41

2.02 (-2.9, 6.93)

P = 0.42

4.45 (-0.04, 8.94)

P = 0.05

Inotropes or vasopressors

4.84 (0.1, 9.57)

P <0.05

3.70 (1.99, 9.40)

P = 0.20

7.63 (0.89, 13.37)

P = 0.01

-4.51 (-9.08, .06)

P = 0.05

0.06 (-4.29, 4.41)

P = 0.98

Antipsychotics

5.81 (0.8, 10.81)

P <0.05

1.59 (-4.31, 7.39)

P = 0.59

1.18 (-4.87, 7.25)

P = 0.70

-1.58 (-6.28, 3.12)

P = 0.51

4.14 (-0.15, 8.43)

P = 0.06

Opioids

-0.55 (-10.42, 9.32)

P = 0.91

-7.12 (-18, 3.77)

P = 0.20

-7.79 (-19.25, 3.66)

P = 0.18

7.42 (-0.96, 15.8)

P = 0.08

0.29 (-7.65, 8.23)

P = 0.94

Steroids

-0.28 (-5.33, 4.77)

P = 0.91

-1.08 (-7.25, 5.08)

P = 0.73

-1.57 (-7.85, 4.71)

P = 0.62

-.59 (-5.48, 4.31)

P = 0.81

5.57 (1.18, 9.96)

P <0.05

Highest C-reactive protein in ICU

0.22

P <0.05

0.10

P = 0.32

0.08

P = 0.44

No data

No data

  1. Effect sizes presented in the table are Pearson's r for normally distributed exposure variables, Spearman's rho for skewed variables, and mean difference with 95% CI for binary variables.
  2. * Range of scores for outcome measures: PTSD 0-51 (PDS); depression 0 to 60 (CES-D); anxiety 0 to 80 (STAI); mental quality of life 0 to 100 (SF-12 mental component summary score); physical quality of life 0 to 100 (SF-12 physical component summary score)
  3. † For type of admission, post-hospital destination and primary body system (categorical variables ) the P-values of the F statistic are presented.
  4. ‡ For all drug variables, the mean score of patients who did not receive the drug group was subtracted from the mean score of patients who did receive the drug.
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Critical Care

ISSN: 1364-8535