Volume 2 Supplement 1
The screen log: a tool for monitoring critical care clinical research activity
© Current Science Ltd 1998
Published: 1 March 1998
Clinical research relevant to the care of critically ill patients has been ongoing for decades. Sponsors of research projects monitor site performance by providing a screen log (SL) which contains a record of enrolled patients (multicentre, uni-project in scope). The present study was undertaken to evaluate the utility of a unicentre, multi-project SL.
Prospective evaluation of an SL for monitoring critical care clinical research activities in a Canadian tertiary care academic medical centre.
Consecutive patients admitted over a 2 year period to the Medical Surgical ICU were screened for eligibility into 3 protocols. Patients were defined as follows: 1. Eligible: met all inclusion criteria; 2. Excluded: study specific exclusion criteria; or prognosis was considered hopeless; or were enrolled in another study; or no consent; or missed; 3. Truly eligible: [eligible]-[met no exclusions + hopeless prognosis + enrolled in other protocol]; 4. Enrolled: consent obtained and patient randomized; 5. Recruitment efficiency: number of patients enrolled / number truly eligible.
54 patients/month were screened for a total of 1292 admissions. Table 1 presents screening and recruitment summary for 3 protocols in progress over varying lengths of time within the 2 year period of SL evaluation.
Total eligible (% of total screened)
Total excluded (% of eligible)
study specific exclusion