Table 2 Clinical parameters were compared between RIARDS and persistent ARDS. Ventilatory parameters significantly differed between persistent ARDS and RIARDS. Steroids were more commonly administered to persistent ARDS patients compared to RIARDS over the first 48 hours of ARDS diagnosis. Bacteremia was more common in persistent ARDS
From: Rapidly improving ARDS differs clinically and biologically from persistent ARDS
|  | Persistent ARDS N = 169 | RIARDS N = 46 | p value | |
|---|---|---|---|---|
Clinical parameters | ||||
Ventilatory parameters on day 1 of ARDS diagnosis | ||||
 Plateau pressure (cmH2O), median (IQR)†| 24 (20, 28) | 20 (17, 21) | 0.0003 | |
 PIP (cmH2O), median (IQR)†| 31 (26, 37) | 26 (22, 31) | 0.001 | |
 FiO2 (%), median (IQR) †| 1 (0.6, 1) | 0.6 (0.5, 0.9) | 0.001 | |
 PEEP (cmH2O), median (IQR) | 5 (5, 10) | 5 (5, 8) | 0.01 | |
 paCO2 (mmHg), median (IQR) | 41 (33, 52) | 44 (33, 49) | 0.84 | |
Arterial pressure on day 1 of ARDS diagnosis | ||||
 MAP (mmHg), median (IQR) | 78 (68, 93) | 76 (67, 90) | 0.50 | |
 SBP (mmHg), median (IQR) | 113 (98, 132) | 110 (99, 126) | 0.52 | |
Medications received within 48 h of ARDS diagnosis | ||||
 Steroids, n (%) | 65 (38) | 6 (13) | 0.001* | |
 Diuretics, n (%) | 35 (21) | 13 (28) | 0.28* | |
 Antibiotics, n (%) | 161 (95) | 45 (98) | 0.44* | |
 Antivirals, n (%) | 41 (24) | 9 (20) | 0.50* | |
 Antifungals, n (%) | 17 (10) | 1 (2) | 0.13 | |
Microbiology within 48 h of ARDS diagnosis | ||||
 Pulmonary infection |  |  |  | |
 Bacterial, n (%) | 33 (20) | 6 (13) | 0.31* | |
 Viral, n (%) | 14 (8) | 7 (15) | 0.16* | |
 Fungal, n (%) | 0 (0) | 0 (0) | – | |
 Bacteremia, n (%) | 30 (18) | 2 (4) | 0.02 | |