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Table 2 Microorganisms responsible for ECMO associated infections by infection site

From: Healthcare-associated infections in patients with severe COVID-19 supported with extracorporeal membrane oxygenation: a nationwide cohort study

Microorganisms

Bloodstream infection

(n = 154)

Ventilator associated Pneumonia

(n = 117)

P value

Crude mortality (%)

Enterobacteriaceae

52 (33.8)

56 (47.9)

0.026

52

 ESBL-PE

6 (3.9)

8 (6.8)

0.420

36

 3rd generation cephalosporin-resistant

31 (20.1)

5 (12.8)

0.141

36

Enterococcus sp.

39 (25.3)

7 (6.0)

 < 0.001

63

 Vancomycin-resistant Enterococcus species

1 (0.6)

0 (0.0)

1.000

100

Non-fermenting Gram negative Bacilli

20 (13.0)

23 (19.7)

0.187

79

 Imipenem-resistant Acinetobacter sp.

1 (0.6)

0 (0.0)

1.000

100

 MDR Pseudomonas sp.

0 (0.0)

1 (0.9)

0.432

0

Coagulase negative Staphylococcus

35 (22.7)

4 (3.4)

 < 0.001

54

Staphylococcus aureus

11 (7.1)

25 (21.4)

0.001

53

 Methicillin-resistant Staphylococcus aureus

4 (2.6)

4 (3.4)

0.729

37

Fungi

15 (9.7)

4 (3.4)

0.075

58

Streptococcus sp.

5 (3.2)

6 (5.1)

0.641

36

Others

9 (5.8)

8 (6.8)

0.935

53

MDR microorganisms

33 (21.4)

18 (15.4)

0.270

41

Polymicrobial

31 (20.1)

16 (13.7)

0.219

55

  1. Results are presented as n(%)
  2. ECMO extracorporeal membrane oxygenation, ESBL-PE extended-spectrum beta-lactamase-producing Enterobacteriaceae, MDR multidrug resistant
  3. *All VAP related to fungi were Pulmonary aspergillosis (Aspergillus fumigatus n = 3 and Aspergillus sp. n = 1) while all BSI related to fungi were Candidemia (Candida albicans n = 7 and Candida sp. n = 8)