Skip to main content
Fig. 5 | Critical Care

Fig. 5

From: The protective effect of apolipoprotein H in paediatric sepsis

Fig. 5

APOH has minimal influence on bacterial phagocytosis and killing capacities upon Pseudomonas aeruginosa infection. a CFU levels in septic mice treated with rAPOH compared with mice treated with BSA after CLP (n = 7). b The proportions of different cell types were observed in the BSA and rAPOH groups (n = 7). c Killing rates were determined in the P.a and P.a + rAPOH groups. d Immunofluorescence was employed to detect the effect of APOH on macrophage phagocytosis. e Relative fluorescence intensity of FITC-labelled P.a in the P.a. and P.a + rAPOH groups. The data are presented as the means ± standard deviations (S.D.). “*” indicates a difference between groups. *p < 0.05, **p < 0.01. Apolipoprotein H, APOH; recombinant APOH, rAPOH; Bacterial colony-forming unit, CFU; caecal ligation and puncture, CLP; fluorescein isothiocyanate, FITC; peritoneal macrophages, PMs; peritoneal lavage fluids, PLFs; peripheral blood mononuclear cells, PBMCs; Pseudomonas aeruginosa, P.a.; tetramethylrhodamine-5-isothiocyanate, TRIC

Back to article page