Table 1 Characteristics of matched patients whether or not they received selective digestive decontamination
All patients n = 5862 | Standard care n = 2931 | SDD n = 2931 | SMD | |
|---|---|---|---|---|
Year of ICU admission | ||||
2017 | 895 (15.3) | 444 (15.1) | 451 (15.4) | 0.0067 |
2018 | 817 (13.9) | 407 (13.9) | 410 (14.0) | 0.0030 |
2019 | 652 (11.1) | 313 (10.7) | 339 (11.6) | 0.0280 |
2020 | 460 (7.8) | 220 (7.5) | 240 (8.2) | 0.0252 |
2021 | 1092 (18.6) | 560 (19.1) | 532 (18.2) | −0.0250 |
2022 | 1946 (33.2) | 987 (33.7) | 959 (32.7) | −0.0201 |
Season of ICU admission | ||||
Spring | 1397 (23.8) | 711 (24.3) | 686 (23.4) | −0.0203 |
Summer | 1446 (24.7) | 690 (23.5) | 756 (25.8) | 0.0513 |
Fall | 1678 (28.6) | 850 (29.0) | 828 (28.2) | −0.0166 |
Winter | 1341 (22.9) | 680 (23.2) | 661 (22.6) | −0.0156 |
Type of ICU | ||||
Medical-surgical (vs surgical) | 5118 (87.3) | 2538 (86.6) | 2580 (88.0) | 0.0446 |
Baseline characteristics | ||||
Age (years) | 63 [50–72] | 63 [50–73] | 63 [50–72] | −0.0292 |
Male sex | 4024 (68.7) | 2003 (68.3) | 2021 (69.0) | 0.0133 |
Immunosuppression | ||||
No immunodepression | 5228 (89.2) | 2614 (89.2) | 2614 (89.2) | 0.0000 |
Neutropenia | 249 (4.2) | 122 (4.2) | 127 (4.3) | 0.0077 |
Other immunosuppression | 385 (6.6) | 195 (6.7) | 190 (6.5) | −0.0070 |
Simplified acute physiology score II | 54 [40–68] | 55 [41–68] | 54 [40–68] | −0.0547 |
Reason for ICU admission: Trauma | 1523 (26.0) | 764 (26.1) | 759 (25.9) | −0.0038 |
Type of admission | ||||
Medical | 3417 (58.3) | 1720 (58.7) | 1697 (57.9) | −0.0158 |
Elective surgery | 341 (5.8) | 168 (5.7) | 173 (5.9) | 0.0073 |
Emergency surgery | 2104 (35.9) | 1043 (35.6) | 1061 (36.2) | 0.0127 |
COVID 19 | 468 (8.0) | 237 (8.1) | 231 (7.9) | −0.0077 |
Provenance from community or nursing home | 3941 (67.2) | 1959 (66.8) | 1982 (67.6) | 0.0169 |
Clinical course | ||||
Antibiotherapy at admission | 2946 (50.3) | 1488 (50.8) | 1458 (49.7) | −0.0205 |
Central venous catheter | 5162 (88.1) | 2587 (88.3) | 2575 (87.9) | −0.0126 |