Table 4 Subgroups analyses
From: Prognostic value of capillary refill time in adult patients: a systematic review with meta-analysis
Subgroups | Number of studies | Number of Patients | AUC ROC | 95%CI | OR | 95%CI | Tau2 | I2 (%) | P value | |
|---|---|---|---|---|---|---|---|---|---|---|
Quality of CRT | High | 5 | 451 | 0.84 | [0.81; 0.87] | 13.9 | [3.6; 53.3] | 0.76 | 64 | 0.009 |
Low | 18 | 60,109 | 0.72 | [0.71; 0.72] | 3.3 | [1.9; 5.6] | 0.94 | 97 | ||
Stopwatch used | YES | 12 | 2816 | 0.77 | [0.75; 0.80] | 5 | [1.9; 12.7] | 1.72 | 80 | 0.686 |
NO | 11 | 57,744 | 0.72 | [0.72; 0.72] | 4 | [2.0; 7.9] | 0.92 | 98 | ||
Location of CRT | Finger | 18 | 40,829 | 0.72 | [0.72; 0.72] | 4.6 | [2.5; 8.5] | 1.16 | 96 | 0.663 |
Other | 5 | 19,731 | 0.71 | [0.66; 0.75] | 3.5 | [0.8; 15.8] | 0.66 | 71 | ||
Reproducible compression technic used | YES | 3 | 165 | 0.83 | [0.76; 0.90] | 10.8 | [2.2; 54.0] | 0 | 0 | 0.025 |
NO | 20 | 60,395 | 0.72 | [0.72; 0.72] | 3.8 | [2.2; 6.8] | 0.95 | 96 | ||
Number of averaged CRT | 2 or more | 6 | 481 | 0.83 | [0.80; 0.86] | 11.3 | [3.5; 36.5] | 0.73 | 62 | 0.019 |
one | 17 | 60,079 | 0.72 | [0.71; 0.72] | 3.2 | [1.8; 5.8] | 0.95 | 97 | ||
Outcome | Vital status | 18 | 40,305 | 0.72 | [0.72; 0.72] | 4.2 | [2.2; 8.2] | 1.23 | 96 | 0.922 |
Adverse events | 5 | 20,255 | 0.70 | [0.66; 0.75] | 4 | [1.7; 9.7] | 0.2 | 66 | ||
Septic Shock | YES | 11 | 792 | 0.77 | [0.74; 0.80] | 3.4 | [1.2; 10.1] | 1.94 | 82 | 0.423 |
NO | 12 | 59,768 | 0.72 | [0.72; 0.72] | 5.3 | [3.0; 9.3] | 0.9 | 98 | ||
Setting | ICU | 10 | 670 | 0.82 | [0.79; 0.85] | 3.9 | [1.3; 11.3] | 1.74 | 81 | 0.705 |
Non ICU | 13 | 59,890 | 0.72 | [0.72; 0.72] | 4.8 | [2.6; 9.0] | 0.93 | 97 | ||
Risk of bias and applicability concern | High | 11 | 40,340 | 0.78 | [0.77; 0.78] | 3.7 | [1.6; 8.8] | 1.47 | 97 | 0.81 |
Low | 12 | 20,220 | 0.62 | [0.61; 0.62] | 4.2 | [2.1; 8.6] | 0.28 | 77 | ||
Resuscitation status | After resuscitation | 11 | 20,135 | 0.70 | [0.66; 0.75] | 4.9 | [2.0; 11.6] | 1.20 | 98 | 0.526 |
Other | 12 | 40,425 | 0.72 | [0.72; 0.72] | 3.5 | [1.8; 6.9] | 0.35 | 58 | ||
Threshold | 3 s | 12 | 47,933 | 0.67 | [0.67 0.67] | 3.6227 | [2.0; 6.7] | 0.70 | 96 | 0.389 |
Other value | 11 | 12,627 | 0.80 | [0.79; 0.81] | 5.7 | [2.1; 15.6] | 1.7 | 92 |