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Fig. 5 | Critical Care

Fig. 5

From: Modulation of mitochondrial function with near-infrared light reduces brain injury in a translational model of cardiac arrest

Fig. 5

Neuroprotective effect of NIR. A The experimental protocol for cardiac arrest, resuscitation and recovery in porcine. B Micrographs showing cresyl violet staining of the hippocampus (2.5× magnification) and random regions in the CA1 and CA3 hippocampus (inset, 20× magnification). C Stereological quantification of remaining neurons in the CA1/CA3 regions of the hippocampus. The sum of neurons and tissue volume were quantified in the hippocampus bilaterally to acquire the density of neurons (cells/mm3). D Neurologic deficit score was recorded four days after arrest. Sham, n = 10; CA/CPR, n = 11 (2 did not achieve ROSC) and CA/CPR + NIR, n = 9. The mean number of neurons and neurologic severity score for each group are represented and were compared with Newman–Keuls multiple comparison test, *p < 0.05, **p < 0.01

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Critical Care

ISSN: 1364-8535