From: Return to work after hospitalization for sepsis: a nationwide, registry-based cohort study
Variable | Person year (py) at risk | Events | Rate per py | Crude HR | Adjusteda HR (95% C) |
---|---|---|---|---|---|
Age-group | Â | Â | Â | Â | Â |
 18–29 | 720 | 1 779 | 2.47 | 1.00 | 1.00 (Reference) |
 30–39 | 824 | 1 966 | 2.38 | 0.90 | 0.90 (0.84 − 0.96) |
 40–49 | 1 080 | 2 552 | 2.36 | 0.80 | 0.78 (0.75 − 0.85) |
 50–60 | 1 595 | 3 592 | 2.25 | 0.69 | 0.69 (0.65 − 0.73) |
Sex | Â | Â | Â | Â | Â |
 Male | 2 579 | 5 939 | 2.30 | 1.00 | 1.00 (Reference) |
 Female | 1 639 | 3 950 | 2.41 | 1.03 | 1.01 (0.97 − 1.05) |
ICU treatmentb | Â | Â | Â | Â | Â |
 No | 2 335 | 5 974 | 2.56 | 1.00 | 1.00 (Reference) |
 Yes | 396 | 660 | 1.67 | 0.57 | 0.56 (0.52 − 0.61) |
Sepsis subgroupc | Â | Â | Â | Â | Â |
 Sepsis | 362 | 989 | 2.73 | 1.00 | 1.00 (Reference) |
 COVID-19-related | 95 | 324 | 3.41 | 1.25 | 1.31 (1.15 − 1.49) |
Site of infectiond | Â | Â | Â | Â | Â |
 Respiratory | 988 | 2 462 | 2.49 | 1.00 | 1.00 (Reference) |
 Genitourinary | 260 | 785 | 3.01 | 1.40 | 1.38 (1.27 − 1.50) |
 Intra-abdominal | 162 | 391 | 2.41 | 1.03 | 1.03 (0.92 − 1.14) |
 Gastrointestinal infections | 169 | 637 | 3.80 | 1.69 | 1.64 (1.51 − 1.79) |
 Skin and soft tissue | 105 | 276 | 2.64 | 1.26 | 1.27 (1.12 − 1.44) |
 Infections following a procedure | 136 | 244 | 1.80 | 0.83 | 0.84 (0.73 − 0.96) |
 Endocarditis/myocarditis | 46 | 74 | 1.60 | 0.70 | 0.70 (0.56 − 0.88) |
 Other infectionse | 793 | 1 800 | 2.27 | 1.00 | 0.96 (0.91 − 1.02) |
Comorbiditiesd | Â | Â | Â | Â | Â |
 Heart and vascular | 652 | 1 175 | 1.80 | 1.00 | 1.00 (Reference) |
 Cancer | 749 | 736 | 0.98 | 0.52 | 0.52 (0.48 − 0.58) |
 Lung | 139 | 367 | 2.65 | 1.57 | 1.60 (1.42 − 1.80) |
 Diabetes | 97 | 269 | 2.80 | 1.58 | 1.58 (1.39 − 1.81) |
 Renal | 17 | 25 | 1.48 | 0.99 | 0.98 (0.66 − 1.46) |
 Immune | 29 | 99 | 3.42 | 2.07 | 2.06 (1.67 − 2.53) |
 Liver | 5 | 10 | 2.03 | 0.60 | 0.62 (0.33 − 1.15) |
No. of comorbidities | Â | Â | Â | Â | Â |
 0 | 2 113 | 6 598 | 3.12 | 1.00 | 1.00 (Reference) |
 1 | 1 687 | 2 681 | 1.59 | 0.45 | 0.46 (0.44 − 0.48) |
 2 | 377 | 547 | 1.45 | 0.38 | 0.39 (0.36 − 0.42) |
  ≥ 3 | 41 | 63 | 1.55 | 0.30 | 0.32 (0.25 − 0.41) |
Type of acute organ dysfunctiond | Â | Â | Â | Â | Â |
 Respiratory | 819 | 1 858 | 2.27 | 1.00 | 1.00 (Reference) |
 Renal | 563 | 1 761 | 3.12 | 1.45 | 1.48 (1.39 − 1.58) |
 Circulatory | 187 | 353 | 1.89 | 0.89 | 0.91 (0.82 − 1.03) |
 Coagulation | 332 | 407 | 1.23 | 0.62 | 0.64 (0.58 − 0.71) |
 Hepatic | 37 | 66 | 1.79 | 0.83 | 0.82 (0.64 − 1.04) |
 Other acute organ dysfunctionsf | 275 | 735 | 2.67 | 1.33 | 1.30 (1.19 − 1.41) |
No. of acute organ dysfunctions | Â | Â | Â | Â | Â |
 1 | 2 214 | 5 180 | 2.34 | 1.00 | 1.00 (Reference) |
 2 | 337 | 492 | 1.46 | 0.60 | 0.60 (0.55 − 0.66) |
 3 | 82 | 109 | 1.33 | 0.57 | 0.56 (0.46 − 0.68) |
  ≥ 4 | 18 | 25 | 1.42 | 0.49 | 0.49 (0.33 − 0.72) |