Table 2 Baseline characteristics according to natremia category
Normonatremia (n = 893) | Hyponatremia (n = 211) | Hypernatemia (n = 31) | |
|---|---|---|---|
Males, n (%) | 651 (72.9) | 156 (73.9) | 19 (61.3) |
Age, years, mean ± SD | 62.9 ± 13.2 | 63.2 ± 12.2 | 60.1 ± 18.3 |
Height, cm, mean ± SD | 172.9 ± 10.5 | 172.1 ± 8.8 | 168.4 ± 10.2 |
Weight, Kg, mean ± SD | 83.3 ± 18.9 | 80.0 ± 18.2 | 75.2 ± 22.9 |
Body Mass Index, Kg·m2, mean ± SD | 28.2 ± 12.3 | 27.3 ± 6.0 | 27.3 ± 7.9 |
Glasgow Coma Scale score at enrolment, median [Q1–Q3] | 3.0 [3.0–3.0] | 3.0 [3.0–3.0] | 3.0 [3.0–3.0] |
Cardiac cause of arrest, n (%) | 596 (66.7) | 121 (57.3) | 8 (25.8) |
Shockable rhythm, n (%) | 452 (50.6) | 80 (37.9) | 4 (12.9) |
Chronic heart disease, n (%) | 390 (43.7) | 112 (53.1) | 12 (38.7) |
Chronic pulmonary disease, n (%) | 168 (18.8) | 70 (33.2) | 7 (22.6) |
Bystander witnessed cardiac arrest, n (%) | 848 (95.0) | 195 (92.9) | 29 (93.5) |
Bystander performed CPR, n (%) | 674 (75.6) | 149 (71.0) | 26 (83.9) |
Location at cardiac arrest | |||
Place of residence, n (%) | 478 (53.5) | 102 (48.3) | 8 (25.8) |
Public place, n (%) | 315 (35.3) | 68 (32.2) | 10 (32.3) |
Hospital, n (%) | 100 (11.2) | 41 (19.4) | 13 (41.9) |
Body temperature, °C, mean ± SD | 35.2 ± 1.3 | 35.2 ± 1.5 | 35.2 ± 1.7 |
SAPSII, mean ± SD | 69.0 ± 17.7 | 72.2 ± 17.5 | 78.0 ± 14.0 |
No-flow duration minutes, median [Q1–Q3] | 0.0 [0.0–5.0] | 0.0 [0.0–5.0] | 0.5 [0.0–5.0] |
Low-flow duration minutes, median [Q1–Q3] | 18.0 [12.0–26.0] | 18.0 [10.0–25.0] | 21.0 [10.0–32.0] |
Time to ROSC, minutes, median [Q1–Q3] | 20.0 [15.0–28.0] | 21.0 [15.0–30.0] | 20.5 [11.0–39.0] |
Epinephrine injection performed, n (%) | 618 (77.4) | 157 (84.4) | 29 (93.5) |
Epinephrine dose, mg, median [Q1–Q3] | 2.0 [0.0–4.0] | 2.0 [1.0–4.0] | 4.0 [2.0–6.0] |
Amiodarone injection, n (%) | 216 (27.1) | 32 (17.2) | 2 (6.5) |
Bicarbonate injection, n (%) | 40 (5.0) | 9 (4.8) | 8 (25.8) |
Vasopressor at inclusion n (%) | 336 (56.2) | 97 (58.8) | 22 (81.5) |
ST-elevation myocardial infarction n (%) | 365 (41.7) | 66 (32.2) | 5 (17.9) |
Coronary angiography, n (%) | 480 (53.8) | 104 (49.3) | 4 (12.9) |
Successful angioplasty, n (%) | 215 (24.1) | 42 (19.9) | 2 (6.5) |
Admission pH, median [Q1–Q3] | 7.3 [7.2–7.3] | 7.3 [7.2–7.3] | 7.2 [7.0–7.3] |
Lactates, mmol/L, median [Q1–Q3] | 3.4 [1.8–6.7] | 3.9 [1.9–7.2] | 9.4 [4.8–14.6] |
Serum creatinine, µmol/L, median [Q1–Q3] | 100.0 [80.0–129.0] | 103.0 [78.0–143.0] | 137.0 [86.0–183.0] |
Blood glucose, mmol/L, mean ± SD | 11.9 ± 5.4 | 13.9 ± 10.2 | 11.9 ± 8.0 |
PaCO2, mmHg, mean ± SD | 45.8 ± 13.1 | 45.1 ± 16.9 | 50.1 ± 19.0 |
PaO2, mmHg, mean ± SD | 169.3 ± 113.8 | 171.7 ± 117.2 | 202.4 ± 140.8 |
NSE on day 2, ng/mL, median [Q1–Q3] | 23.9 [18.0–35.8] | 24.0 [17.4–35.0] | 63.4 [9.0–90.2] |
NSE on day 3, ng/mL, median [Q1–Q3] | 20.9 [14.7–44.0] | 21.7 [15.4–48.5] | 26.9 [5.9–33.9] |
Potassium, mmol/L, mean ± SD | 4.2 ± 0.9 | 4.7 ± 1.1 | 4.7 ± 1.5 |
Urea, mmol/L, mean ± SD | 8.4 ± 6.1 | 9.7 ± 10.9 | 11.3 ± 8.9 |
Normo-osmolality, n (%) | 414 (75.5) | 75 (48.4) | 1 (3.7) |
Hypo-osmolality, n (%) | 2 (0.4) | 78 (50.3) | 0 (0.0) |
Hyperosmolality, n (%) | 132 (24.1) | 2 (1.3) | 26 (96.3) |
mCAHP score, median [Q1–Q3] | 90.6 [71.2–106.8] | 91.4 [79.0–105.5] | 96.0 [84.3–109.3] |