Fig. 4
From: Human cytomegalovirus seropositivity is associated with reduced patient survival during sepsis
The plasma proteomics analysis according to survival. a Dot-plot illustrating the statistical analysis of n = 66 HCMV seronegative and n = 105 seropositive patients at days 1 and 4 (Student’s t-test; two-sided, unequal variances). b Volcano plot illustrating plasma proteome quantitation for seropositive patients and days 1 and 4 (p-values corrected according to Benjamini-Hochberg). Significantly regulated proteins (pFDR value ≤ 0.05, absolute ratio of means ≥ 1.5) highlighted in red and labeled with gene names. c Gene ontology enrichment analysis of proteins regulated in seropositive patients at day 4 (p-value ≤ 0.05, absolute ratio of means ≥ 1.5). d Network representation of regulated proteins passing the pFDR threshold of 0.05. Selected enriched ontologies (biological process) highlighted. e Scatter plots illustrating plasma proteome dynamics at day 4 for HCMV seronegative and seropositive patients. Proteins significantly regulated in seropositive patients are highlighted in both plots