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Table 4 Selection of cefoxitin-resistant bacterial strains at 30 days on any sample after administration of cefoxitin or carbapenem

From: Cefoxitin versus carbapenems as definitive treatment for extended-spectrum β-lactamase-producing Klebsiella pneumoniae bacteremia in intensive care unit: a propensity-matched retrospective analysis

Characteristic

Cefoxitin

n = 63

Carbapenem

n = 47

p value

Selection of at least one cefoxitin-resistant gram-negative bacteria at 30 days

30 (48)

22 (47)

.933

Klebsiella pneumoniae cefoxitin-resistant

7 (11)

4 (8)

.755

 Including colonization

4 (6)

1 (2)

 

 Including infection

3 (5)

3 (6)

 

AmpC β-lactamase-producing Enterobacterales

15 (24)

2 (4)

.006

 Including colonization

6 (9)

0 (0)

 

 Including infection

9 (14)

2 (4)

 

Pseudomonas aeruginosa

13 (21)

18 (38)

.042

 Including colonization

3 (5)

8 (17)

 

 Including infection

10 (16)

10 (21)

 

Pseudomonas aeruginosa carbapenem-resistant

3 (5)

11 (23)

.007

 Including colonization

2 (3)

5 (11)

 

 Including infection

1 (2)

6 (13)

 

Stenotrophomonas maltophilia

0 (0)

1 (2)

.427

Acinetobacter baumannii

2 (3)

0 (0)

1.00

  1. Date are presented as count (%). P values in bold are statistically significant