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Table 2 Outcomes of patients with ESBL-KP bacteremia according to antibiotic treatment

From: Cefoxitin versus carbapenems as definitive treatment for extended-spectrum β-lactamase-producing Klebsiella pneumoniae bacteremia in intensive care unit: a propensity-matched retrospective analysis

Outcomes

Cefoxitin

(n = 63)

Carbapenem

(n = 47)

Univariate analysis

PS-adjusted analysis

(n = 100)

HR (95%CI)

p value

aHR (95%CI)

p value

30-day clinical success

36 (57)

25 (53)

0.9 (0.5–1.6)

.823

1.3 (0.6–2.5)

.497

 30-day all-cause mortality

18 (29)

20 (42)

0.6 (0.3–1.2)

.131

0.8 (0.4–1.7)

.549

 Relapse

6 (11)

4 (11)

1.1 (0.3–3.9)

.887

0.8 (0.1–4.0)

.768

 Change of antibiotic

11 (17)

0 (0)

N/A

.002

N/A

N/A

7-day all-cause mortality

9 (14)

7 (15)

0.9 (0.3–2.5)

.889

1.5 (0.5–4.8)

.463

Microbiological failure

10 (16)

7 (15)

1.1 (0.4–2.8)

.897

1.6 (0.5–5.3)

.414

  1. Data are presented as median [IQR] or count (%). p values in bold are statistically significant. aHR = adjusted hazard ratio. N/A = not applicable
  2. *Fisher's exact test used for this variable for which one of the counts is 0