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Table 1 Demographic and prehospital data stratified according to survival status after 365 days

From: Serial assessments of cardiac output and mixed venous oxygen saturation in comatose patients after out-of-hospital cardiac arrest

 

Total population

Survivors at 365 days

Deceased at 365 days

p-value

 

n = 565

n = 470 (65%)

n = 248 (35%)

 

Demography

 Age—year (± SD)

62 ± 13

60 ± 14

67 ± 12

 < 0.0001

 Male gender—n (%)

458 (81%)

305 (82%)

153 (79%)

0.34

Randomization allocation

 MAP at 63 mmHg—n (%)

279 (51%)

185 (51%)

94 (49%)

0.69

 PaO2 at 9–10 kPa—n (%)

284 (50%)

191 (51%)

93 (48%)

0.48

Cardiac arrest characteristics

 Witnessed arrest—n (%)

466 (85%)

314 (87%)

152 (80%)

0.03

 Bystander CPR—n (%)

501 (88%)

343 (92%)

158 (81%)

 < 0.0001

 Bystander defibrillation—n (%)

125 (23%)

90 (24%)

35 (19%)

0.09

 Shockable primary rhythm—n (%)

460 (84%)

312 (87%)

148 (76%)

0.0001

 Time to ROSC—min. (Q1–Q3)

18 (12–26)

15 (10–20)

25 (17–33)

 < 0.0001

 Lactate at admission—mmol/L. (Q1-Q3)

5 (2.9–7.7)

3.9 (2.3–6.8)

6.0 (4.1–9.4)

 < 0.0001

 Acute CAG

513 (91%)

331 (89%)

182 (94%)

0.09

 PCI—n (%)

229 (41%)

149 (40%)

80 (41%)

0.80

LVEF at hospital admission

35 ± 14

37 ± 14

34 ± 14

0.03

Pre-arrest comorbidities

 Previous AMI—n (%)

121 (21%)

73 (20%)

48 (25%)

0.09

 Congestive heart failure—n (%)

105 (19%)

51 (15%)

54 (28%)

0.004

 Hypertension—n (%)

272 (48%)

164 (44%)

108 (56%)

0.009

 Previous TCI/stroke—n (%)

41 (7%)

24 (7%)

17 (9%)

0.28

 Diabetes—n (%)

80 (14%)

41 (11%)

349(20%)

0.003

 Chronic obstructive pulmonary disease—n (%)

46 (8%)

21 (6%)

25 (13%)

0.01

 Chronic kidney disease—n (%)

24 (4%)

14 (4%)

10 (6%)

0.19

 Atrial fibrillation—n (%)

99 (18%)

49 (13%)

50 (25%)

0.0002

Time intervals

 Time from arrest to ICU admission—h (q1–q3)

2.4 (1.9–3.1)

2.4 (1.9–3.1)

2.5 (1.9–3.1)

0.46

 Time from arrest to PAC insertion—h (q1–q3)

3.0 (2.0–3.0)

3.0 (2.0–3.0)

3.0 (2.0–3.0)

0.63

  1. CAG, coronary angiography; CPR, cardiopulmonary resuscitation; Q1–Q3, interquartile range; LVEF, left ventricular ejection fraction; n, number; PCI, percutaneous coronary intervention; ROSC, return of spontaneous circulation; SD, standard deviation; TCI, transitory cerebral ischemia; MAP, mean arterial blood pressure; PaO2, partial pressure of oxygen in arterial blood; kPa, kilo pascal. Bold indicates statistical significance which is a p-value below 0.05