Table 1 Characteristics of patients’ stays and implementation of the POINCARE-2 strategy

Duration of stays in icu (days)

Kruskal–Wallis: 0.020

 N

73

284

369

610

1336

 Mean (std)

14.1 (10.84)

15.0 (10.48)

13.5 (9.83)

15.9 (11.76)

15.0 (10.98)

 Min–median–max

2–11.0–58

4–12.0–58

3–11.0–56

2–12.0–60

2–11.0–60

 2

1 (1.4%)

0 (0.0%)

0 (0.0%)

1 (0.2%)

2 (0.1%)

 3

7 (9.5%)

0 (0.0%)

6 (1.6%)

7 (1.1%)

20 (1.5%)

 4

5 (6.8%)

22 (7.6%)

23 (6.1%)

15 (2.4%)

65 (4.8%)

 5

0 (0.0%)

18 (6.3%)

19 (5.1%)

50 (8.0%)

87 (6.4%)

 6

7 (9.5%)

20 (6.9%)

22 (5.9%)

42 (6.7%)

91 (6.7%)

 7

3 (4.1%)

10 (3.5%)

42 (11.2%)

35 (5.6%)

90 (6.6%)

 8

5 (6.8%)

13 (4.5%)

30 (8.0%)

32 (5.1%)

80 (5.9%)

 9

2 (2.7%)

16 (5.6%)

19 (5.1%)

44 (7.1%)

81 (6.0%)

 10

5 (6.8%)

24 (8.3%)

23 (6.1%)

34 (5.4%)

86 (6.3%)

 11

2 (2.7%)

18 (6.3%)

22 (5.9%)

37 (5.9%)

79 (5.8%)

 12

3 (4.1%)

10 (3.5%)

16 (4.3%)

23 (3.7%)

52 (3.8%)

 13

3 (4.1%)

10 (3.5%)

22 (5.9%)

28 (4.5%)

63 (4.6%)

 14 or more

31 (41.9%)

127 (44.1%)

131 (34.9%)

276 (44.2%)

565 (41.5%)

Extra-renal purification during d0-14

8 (10.8%)

37 (12.8%)

64 (17.1%)

180 (28.8%)

289 (21.2%)

Chi-2: < 0.001

 Total ultrafiltration from day 0 to day 14 (ml)

  N

5

29

54

155

243

  Mean (std)

941.8 (549.09)

5900.4 (7994.25)

7621.5 (7286.60)

12098.5 (10496.76)

10134.4 (9844.67)

  Min–median–max

250–1000.0–1740

120–4200.0–39976

28–4866.0–30033

50–9824.0–56181

28–7156.0–56181

Average daily fluid intake from day 0 to day 14 (ml)

F-test: 0.249

 N

74

288

375

624

1361

 Mean (std)

2297.7 (723.21)

2469.1 (871.77)

2478.4 (858.66)

2404.2 (860.61)

2432.6 (855.99)

 Min–median–max

254–2189.9–4487

377–2345.1–7233

239–2420.3–5411

469–2292.4–5913

239–2328.3–7233

Total dose of albumin 20% from day 0 to day 14 (ml)

Kruskal–Wallis: 0.016

 N

12

48

51

91

202

 Mean (std)

583.3 (404.15)

471.9 (372.59)

672.5 (643.14)

818.7 (803.73)

685.4 (673.15)

 Min–median–max

100–450.0–1500

100–300.0–1500

100–400.0–3700

100–600.0–5100

100–500.0–5100

Total dose of diuretics from day 0 to day 14 (mg)

Kruskal–Wallis: < 0.001

 N

45

160

263

485

953

 Mean (std)

408.4 (1208.74)

326.0 (515.01)

665.6 (1605.31)

770.7 (1414.45)

649.9 (1366.05)

 Min–median–max

10–120.0–8140

20–140.0–3500

10–210.0–12636

20–300.0–13432

10–220.0–13432

Contraindications

65 (87.8%)

252 (87.5%)

349 (93.1%)

590 (94.6%)

1256 (92.3%)

Chi-2: 0.001

 At least one fluid vascular loading (over d2-d14)

44 (59.5%)

171 (59.4%)

250 (66.7%)

392 (62.8%)

857 (63.0%)

Chi-2: 0.242

 Arterial hypotension (at least one episode over d2-d14)

45 (60.8%)

204 (70.8%)

287 (76.5%)

488 (78.2%)

1024 (75.2%)

Chi-2: 0.002

 At least one episode of hypernatremia > 155 mmol/l (over d2-d14)

Fisher's Exact: 0.024

  Missing

1

0

2

0

3

  No

67 (90.5%)

284 (98.6%)

362 (96.5%)

600 (96.2%)

1313 (96.5%)

  Yes

6 (8.1%)

4 (1.4%)

11 (2.9%)

24 (3.8%)

45 (3.3%)

 At least one episode of hypokalemia < 2.8 mmol/l (over d2-d14)

Chi-2: 0.715

  Missing

1

0

1

0

2

  No

67 (90.5%)

264 (91.7%)

351 (93.6%)

576 (92.3%)

1258 (92.4%)

  Yes

6 (8.1%)

24 (8.3%)

23 (6.1%)

48 (7.7%)

101 (7.4%)

 At least one episode of non-normal rifle (over d2-d14)

51 (68.9%)

173 (60.1%)

266 (70.9%)

503 (80.6%)

993 (73.0%)

Chi-2: < 0.001

Percentage of weighing done from day 2 to day 14

Kruskal–Wallis: < 0.001

 N

74

288

375

624

1361

 Mean (std)

16.4 (16.16)

47.3 (17.16)

70.0 (13.90)

92.9 (8.35)

72.8 (25.69)

 Min–median–max

0–16.0–92

25–44.4–100

50–66.7–100

75–100.0–100

0–77.8–100