Variables | All N = 112 | RT group N = 28 | HMB group N = 28 | Combined group N = 28 | Control group N = 28 | Statistics | P value |
---|---|---|---|---|---|---|---|
Centre [N(%)] | Â | Â | Â | Â | Â | Â | Â |
 1 | 46(41.1) | 11(39.3) | 9(32.1) | 4(50.0) | 12(42.9) | 7.272 | 0.839 |
 2 | 25(22.3) | 6(21.4) | 6(21.4) | 7(25.0) | 6(21.4) |  |  |
 3 | 23(20.5) | 5(17.9) | 6(21.4) | 7(14.3) | 8(28.6) |  |  |
 4 | 2(1.8) | 1(3.6) | 1(3.6) | 0(0) | 0(0) |  |  |
 5 | 16(14.3) | 5(17.9) | 6(21.4) | 3(10.7) | 2(7.1) |  |  |
Age [years] | 59.87 ± 15.81 | 55.44 ± 15.63 | 62.68 ± 14.29 | 60.04 ± 14.95 | 61.18 ± 18.04 | 1.067 | 0.366 |
Male [N(%)] | 88(78.57) | 23(82.14) | 23(82.14) | 22(78.57) | 20(71.43) | 1.273 | 0.736 |
BMI [kg/m2, N (%)] | 22.82 ± 4.20(rang13.67 to 38.74) | 23.0 ± 3.92(rang 16.14 to 31.14) | 23.01 ± 4.76(rang 14.79 to 38.74) | 22.49 ± 3.19(rang 15.94 to 27.68) | 22.77 ± 4.91(rang 13.67 to 33.27) | 0.093 | 0.964 |
  < 18.5 | 16(14.3) | 4(14.3) | 3(10.7) | 3(10.7) | 6(21.4) | 4.158 | 0.901 |
 18.5–24.9 | 65(58.0) | 16(57.1) | 17(60.7) | 18(64.3) | 14(50.0) |  |  |
 25–29.9 | 25(22.3) | 6(21.4) | 6(21.4) | 7(25.0) | 6(21.4) |  |  |
  ≥ 30 | 6(5.4) | 2(7.1) | 2(7.1) | 0(0) | 2(7.1) |  |  |
Education [N(%)] | Â | Â | Â | Â | Â | Â | Â |
 Illiterate or semi-literate | 21(18.8) | 6(21.4) | 6(21.4) | 5(17.9) | 4(14.3) | 10.942 | 0.280 |
 Elementary School | 31(27.7) | 6(21.4) | 5(17.9) | 8(28.6) | 12(42.9) |  |  |
 Junior to senior high school | 46(41.1) | 14(50.0) | 13(46.4) | 13(46.4) | 6(21.4) |  |  |
 College diploma or above | 14(12.5) | 2(7.1) | 4(14.3) | 2(7.1) | 6(21.4) |  |  |
Work prior to admission | Â | Â | Â | Â | Â | Â | Â |
 None | 12(10.7) | 2(7.1) | 2(7.1) | 6(21.4) | 2(7.1) | 7.693 | 0.261 |
 Physical labour | 29(25.9) | 10(35.7) | 5(17.9) | 5(17.9) | 9(32.1) |  |  |
 Non-physical labour | 71(63.4) | 16(57.1) | 21(75.0) | 17(60.7) | 17(60.7) |  |  |
 Smoking [N(%)] | 48(42.9) | 11(39.3) | 15(53.6) | 11(39.3) | 11(39.3) | 1.750 | 0.626 |
 Drinking [N(%)] | 46(41.4) | 16(57.1) | 11(39.3) | 10(35.7) | 9(33.3) | 4.008 | 0.261 |
 Length of stay prior to ICU [days, M(Q25,Q75)] | 0(0,2.0) | 0(0,1.0) | 0(0,2.75) | 0.5(0,3.0) | 0(0,2.0) | 2.667 | 0.446 |
ICU Patient Sources [N(%)] | Â | Â | Â | Â | Â | Â | Â |
 Emergency | 54(48.2) | 13(46.4) | 14(50.0) | 8(28.6) | 19(67.9) | 12.319 | 0.196 |
 General ward | 30(26.8) | 6(21.4) | 8(28.6) | 11(39.3) | 5(17.9) |  |  |
 Post-operation | 4(3.6) | 2(7.1) | 0(0) | 2(7.1) | 0(0) |  |  |
 Transferred from another hospital | 24(21.4) | 7(25.0) | 6(21.4) | 7(25.0) | 4(14.3) |  |  |
 Plan to be transferred to ICU [N(%)] | 7(6.3) | 4(14.3) | 0(0) | 2(7.1) | 1(3.6) | 5.333 | 0.149 |
Diagnosis [N(%)] | Â | Â | Â | Â | Â | Â | Â |
 Acute and chronic lung diseases | 46(41.1) | 7(25.0) | 11(39.3) | 11(39.3) | 14(60.7) | 14.164 | 0.290 |
 Sepsis | 25(22.3) | 7(25.0) | 8(28.6) | 6(21.4) | 4(14.3) |  |  |
 Chronic kidney disease | 7(6.3) | 3(10.7) | 0(0) | 2(7.1) | 2(7.1) |  |  |
 Acute Pancreatitis | 8(7.1) | 4(14.3) | 1(3.6) | 1(3.6) | 2(7.1) |  |  |
 Others | 26(23.2) | 7(25.0) | 8(28.6) | 8(28.6) | 3(10.7) |  |  |
Complications [N(%)] | Â | Â | Â | Â | Â | Â | Â |
 Respiratory failure | 55(49.1) | 9(32.1) | 16(57.1) | 13(46.4) | 17(60.7) | 5.537 | 0.136 |
 Heart failure | 19(17.0) | 2(7.1) | 7(25.0) | 4(14.3) | 6(21.4) | 3.740 | 0.291 |
 Sepsis | 30(26.8% | 7(25.0) | 9(32.1) | 7(25.0) | 7(25.0) | 0.546 | 0.909 |
 Multiple organ failure | 8(7.1) | 0(0) | 5(17.9) | 1(3.6) | 2(7.1) | 7.538 | 0.057 |
Charlson Comorbidity Index [M(Q25,Q75)] | 3.0(2.0,5.0) | 2.0(2.0,3.75) | 3.5(2.0,5.0) | 4.0(2.0,5.0) | 3.0(3.0,5.0) | 6.082 | 0.108 |
Oxygenation index at admission [M(Q25,Q75)] | 245.0(178.0,317.50) | 238.0(179.0,363.25) | 281.50(168.25,306.25) | 245.0(177.25,307.50) | 246.0(182.25,315.0) | 0.242 | 0.971 |
APACHEII [M (Q25, Q75)] | 16.0(12.0,23.0) | 13.50(9.50,21.75) | 15.0(10.25,20.50) | 20.0(15.25,25.75) | 15.0(12.25,22.75) | 7.697 | 0.053 |
SOFA [M (Q25, Q75)] | 6.0(4.0,8.0) | 6.0(3.25,7.0) | 6.0(2.50,9.75) | 6.0(4.0,8.75) | 5.0(4.0,6.0) | 0.917 | 0.821 |
NRS2002[M (Q25, Q75)] | 3.0(3.0,4.0) | 3.0(3.0,4.0) | 3.0(3.0,4.75) | 4.0(3.0,4.0) | 4.0(3.0,4.0) | 1.940 | 0.585 |
NUTRIC | 4.32 ± 1.98 | 3.78 ± 1.95 | 4.43 ± 1.81 | 4.86 ± 2.00 | 4.19 ± 2.06 | 1.464 | 0.229 |
Length of ICU stay [days, M (Q25, Q75)] | 6.50(4.0,12.0) | 5.0(3.0,9.75) | 9.0(4.0,17.75) | 6.0(3.0,9.0) | 7.5(5.0,14.0) | 7.430 | 0.059 |
Endotracheal intubation [N(%)] | 34(30.9) | 9(32.1) | 8(30.8) | 8(28.6) | 9(32.1) | 0.112 | 0.990 |
Duration of mechanical ventilation [h, M (Q25, Q75)] | 0(0,41.0) | 0(0,7.0) | 0(0,30.0) | 0(0,34.75) | 0(0,116.75) | 2.046 | 0.563 |
60-Day Mortality [N(%)] | 9(8.0) | 0(0) | 3(10.7) | 3(10.7) | 3(10.7) | 3.262 | 0.353 |
Length of hospital stay [days, M (Q25, Q75)] | 15.0(11.0,27.25) | 14.0(9.25,19.50) | 21.0(11.25,34.75) | 15.50(13,23.75) | 14.0(10.0,36.50) | 5.155 | 0.161 |
Length of hospital stay after ICU [days, M (Q25, Q75)] | 14.0(9.0,22.75) | 13.0(8.25,19.25) | 13.5(10.25,24.25) | 14.0(10.50,22.25) | 13.50(7.25,28.25) | 1.976 | 0.577 |
Duration of ICU stay prior to the study [days, M (Q25, Q75)] | 2.0(2.0,5.0) | 2.0(1.0,7.0) | 3.0(2.0,8.0) | 2.0(1.25,3.0) | 2.50(2.0,5.75) | 5.046 | 0.168 |