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Table 1 Patient characteristics

From: Effects of a multilevel intervention of resistance training with or without beta-hydroxy-beta-methylbutyrate in medical ICU patients during entire hospitalisation: a four-arm multicentre randomised controlled trial

Variables

All N = 112

RT group N = 28

HMB group N = 28

Combined group N = 28

Control group N = 28

Statistics

P value

Centre [N(%)]

       

 1

46(41.1)

11(39.3)

9(32.1)

4(50.0)

12(42.9)

7.272

0.839

 2

25(22.3)

6(21.4)

6(21.4)

7(25.0)

6(21.4)

  

 3

23(20.5)

5(17.9)

6(21.4)

7(14.3)

8(28.6)

  

 4

2(1.8)

1(3.6)

1(3.6)

0(0)

0(0)

  

 5

16(14.3)

5(17.9)

6(21.4)

3(10.7)

2(7.1)

  

Age [years]

59.87 ± 15.81

55.44 ± 15.63

62.68 ± 14.29

60.04 ± 14.95

61.18 ± 18.04

1.067

0.366

Male [N(%)]

88(78.57)

23(82.14)

23(82.14)

22(78.57)

20(71.43)

1.273

0.736

BMI [kg/m2, N (%)]

22.82 ± 4.20(rang13.67 to 38.74)

23.0 ± 3.92(rang 16.14 to 31.14)

23.01 ± 4.76(rang 14.79 to 38.74)

22.49 ± 3.19(rang 15.94 to 27.68)

22.77 ± 4.91(rang 13.67 to 33.27)

0.093

0.964

  < 18.5

16(14.3)

4(14.3)

3(10.7)

3(10.7)

6(21.4)

4.158

0.901

 18.5–24.9

65(58.0)

16(57.1)

17(60.7)

18(64.3)

14(50.0)

  

 25–29.9

25(22.3)

6(21.4)

6(21.4)

7(25.0)

6(21.4)

  

  ≥ 30

6(5.4)

2(7.1)

2(7.1)

0(0)

2(7.1)

  

Education [N(%)]

       

 Illiterate or semi-literate

21(18.8)

6(21.4)

6(21.4)

5(17.9)

4(14.3)

10.942

0.280

 Elementary School

31(27.7)

6(21.4)

5(17.9)

8(28.6)

12(42.9)

  

 Junior to senior high school

46(41.1)

14(50.0)

13(46.4)

13(46.4)

6(21.4)

  

 College diploma or above

14(12.5)

2(7.1)

4(14.3)

2(7.1)

6(21.4)

  

Work prior to admission

       

 None

12(10.7)

2(7.1)

2(7.1)

6(21.4)

2(7.1)

7.693

0.261

 Physical labour

29(25.9)

10(35.7)

5(17.9)

5(17.9)

9(32.1)

  

 Non-physical labour

71(63.4)

16(57.1)

21(75.0)

17(60.7)

17(60.7)

  

 Smoking [N(%)]

48(42.9)

11(39.3)

15(53.6)

11(39.3)

11(39.3)

1.750

0.626

 Drinking [N(%)]

46(41.4)

16(57.1)

11(39.3)

10(35.7)

9(33.3)

4.008

0.261

 Length of stay prior to ICU [days, M(Q25,Q75)]

0(0,2.0)

0(0,1.0)

0(0,2.75)

0.5(0,3.0)

0(0,2.0)

2.667

0.446

ICU Patient Sources [N(%)]

       

 Emergency

54(48.2)

13(46.4)

14(50.0)

8(28.6)

19(67.9)

12.319

0.196

 General ward

30(26.8)

6(21.4)

8(28.6)

11(39.3)

5(17.9)

  

 Post-operation

4(3.6)

2(7.1)

0(0)

2(7.1)

0(0)

  

 Transferred from another hospital

24(21.4)

7(25.0)

6(21.4)

7(25.0)

4(14.3)

  

 Plan to be transferred to ICU [N(%)]

7(6.3)

4(14.3)

0(0)

2(7.1)

1(3.6)

5.333

0.149

Diagnosis [N(%)]

       

 Acute and chronic lung diseases

46(41.1)

7(25.0)

11(39.3)

11(39.3)

14(60.7)

14.164

0.290

 Sepsis

25(22.3)

7(25.0)

8(28.6)

6(21.4)

4(14.3)

  

 Chronic kidney disease

7(6.3)

3(10.7)

0(0)

2(7.1)

2(7.1)

  

 Acute Pancreatitis

8(7.1)

4(14.3)

1(3.6)

1(3.6)

2(7.1)

  

 Others

26(23.2)

7(25.0)

8(28.6)

8(28.6)

3(10.7)

  

Complications [N(%)]

       

 Respiratory failure

55(49.1)

9(32.1)

16(57.1)

13(46.4)

17(60.7)

5.537

0.136

 Heart failure

19(17.0)

2(7.1)

7(25.0)

4(14.3)

6(21.4)

3.740

0.291

 Sepsis

30(26.8%

7(25.0)

9(32.1)

7(25.0)

7(25.0)

0.546

0.909

 Multiple organ failure

8(7.1)

0(0)

5(17.9)

1(3.6)

2(7.1)

7.538

0.057

Charlson Comorbidity Index [M(Q25,Q75)]

3.0(2.0,5.0)

2.0(2.0,3.75)

3.5(2.0,5.0)

4.0(2.0,5.0)

3.0(3.0,5.0)

6.082

0.108

Oxygenation index at admission [M(Q25,Q75)]

245.0(178.0,317.50)

238.0(179.0,363.25)

281.50(168.25,306.25)

245.0(177.25,307.50)

246.0(182.25,315.0)

0.242

0.971

APACHEII [M (Q25, Q75)]

16.0(12.0,23.0)

13.50(9.50,21.75)

15.0(10.25,20.50)

20.0(15.25,25.75)

15.0(12.25,22.75)

7.697

0.053

SOFA [M (Q25, Q75)]

6.0(4.0,8.0)

6.0(3.25,7.0)

6.0(2.50,9.75)

6.0(4.0,8.75)

5.0(4.0,6.0)

0.917

0.821

NRS2002[M (Q25, Q75)]

3.0(3.0,4.0)

3.0(3.0,4.0)

3.0(3.0,4.75)

4.0(3.0,4.0)

4.0(3.0,4.0)

1.940

0.585

NUTRIC

4.32 ± 1.98

3.78 ± 1.95

4.43 ± 1.81

4.86 ± 2.00

4.19 ± 2.06

1.464

0.229

Length of ICU stay [days, M (Q25, Q75)]

6.50(4.0,12.0)

5.0(3.0,9.75)

9.0(4.0,17.75)

6.0(3.0,9.0)

7.5(5.0,14.0)

7.430

0.059

Endotracheal intubation [N(%)]

34(30.9)

9(32.1)

8(30.8)

8(28.6)

9(32.1)

0.112

0.990

Duration of mechanical ventilation [h, M (Q25, Q75)]

0(0,41.0)

0(0,7.0)

0(0,30.0)

0(0,34.75)

0(0,116.75)

2.046

0.563

60-Day Mortality [N(%)]

9(8.0)

0(0)

3(10.7)

3(10.7)

3(10.7)

3.262

0.353

Length of hospital stay [days, M (Q25, Q75)]

15.0(11.0,27.25)

14.0(9.25,19.50)

21.0(11.25,34.75)

15.50(13,23.75)

14.0(10.0,36.50)

5.155

0.161

Length of hospital stay after ICU [days, M (Q25, Q75)]

14.0(9.0,22.75)

13.0(8.25,19.25)

13.5(10.25,24.25)

14.0(10.50,22.25)

13.50(7.25,28.25)

1.976

0.577

Duration of ICU stay prior to the study [days, M (Q25, Q75)]

2.0(2.0,5.0)

2.0(1.0,7.0)

3.0(2.0,8.0)

2.0(1.25,3.0)

2.50(2.0,5.75)

5.046

0.168

  1. BMI: Body Mass Index = Weight / Height^2 (kg/m^2); MODS: Multiple Organ Dysfunction Syndrome; APACHE II: Acute Physiology and Chronic Health Evaluation II; SOFA: Sequential Organ Failure Assessment; NRS2002: Nutritional Risk Screening 2002; NUTRIC: Nutrition Risk in Critically Ill; CCI: Charlson Comorbidity Index