Table 3 Differences in Inflammatory Biomarker Levels between Subclasses 1 and 2
From: Whole blood transcriptomics identifies subclasses of pediatric septic shock
Biomarkers (pg/mL) | Subclass 1 | Subclass 2 | False discovery rate (FDR) adjusted p value†|
|---|---|---|---|
PAI1 | 500 (224–887) | 200 (94–308) | 0.013* |
IL4 | 7919 (3270–11897) | 4510 (1770–10910) | 0.32 |
IL6 | 148 (49–699) | 15 (9–52) |  < 0.001* |
IL8 | 34 (24–217) | 14 (13–20) |  < 0.001* |
IL10 | 13 (10–72) | 10 (7–18) | 0.027* |
ANG2 | 6936 (3255–8587) | 3414 (1901–6216) | 0.035* |
Thrombomodulin | 4891 (4234–6531) | 4144 (3389–5651) | 0.15 |
TFPI | 12,027 (7262–18,706) | 13,440 (7036–17308) | 0.72 |
TREM1 | 489 (330–578) | 325 (258–427) | 0.044* |
P-selectin | 6414 (4880–8740) | 6878 (4623–8885) | 0.93 |
ICAM1 | 130,000 (97,558- 193,000) | 113,000 (80,346- 164,000) | 0.36 |
TNFR-1 | 1833 (1466–2284) | 1106 (932–1296) |  < 0.001* |