Fig. 3

Heatmaps A Heatmap depicting the expression of all 840 differentially expressed genes (DEGs) between septic shock cases and controls. Each row represents a DEG; blue indicates that a gene is downregulated, while red indicates that a gene is upregulated. Each column is a patient, so each column depicts the transcriptomic signature of each patient. The dendrogram at the top shows unsupervised hierarchical clustering of the patients such that the patients with similar transcriptomic signatures are clustered together. B This heatmap depicts the same patients and genes as in Fig. 2A, but now the controls are sorted on the left, and the cases sorted on the right. Clustering based on each patient’s transcriptomic signature was performed within each group