From: Subphenotypes in patients with acute respiratory distress syndrome treated with high-flow oxygen
Overall (n = 41) | Hypoinflammatory subphenotype (n = 24) | Hyperinflammatory subphenotype (n = 17) | p value | |
---|---|---|---|---|
Shock, n (%) | 22 (53.7) | 11 (45.8) | 11 (64.7) | 0.381 |
Renal failure, n (%) | 21 (51.2) | 10 (41.7) | 11 (64.7) | 0.256 |
Need for MV during ICU course, n (%) | 19 (46.3) | 8 (33.3) | 11 (64.7) | 0.096 |
Need for MV at day 3, n (%) | 14 (35.0) | 6 (26.1) | 8 (47.1) | 0.299 |
Need for MV at day 7, n (%) | 16 (40.0) | 7 (30.4) | 9 (52.9) | 0.049 |
Days of MV, median (IQR) (all patients) | 8.5 [6.0, 22.0] | 9.0 [5.0, 23.0] | 8.0 [7.0, 20.0] | 0.916 |
Days of MV, median (IQR) (survivors) | 8.5 [6.5, 20.8] | 9.0 [5.0, 23.0] | 8.0 [7.5, 14.0] | 1.000 |
ICU length of stay, median (IQR) | 28.0 [18.5, 56.5] | 22.0 [18.0, 30.0] | 39.5 [25.5, 60.0] | 0.034 |
60-day mortality, n (%) n = 39 | 10 (25.6) | 2 (9.1) | 8 (47.1) | 0.020 |