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Table 2 Clinical outcomes during ICU course

From: Subphenotypes in patients with acute respiratory distress syndrome treated with high-flow oxygen

 

Overall (n = 41)

Hypoinflammatory subphenotype (n = 24)

Hyperinflammatory subphenotype (n = 17)

p value

Shock, n (%)

22 (53.7)

11 (45.8)

11 (64.7)

0.381

Renal failure, n (%)

21 (51.2)

10 (41.7)

11 (64.7)

0.256

Need for MV during ICU course, n (%)

19 (46.3)

8 (33.3)

11 (64.7)

0.096

Need for MV at day 3, n (%)

14 (35.0)

6 (26.1)

8 (47.1)

0.299

Need for MV at day 7, n (%)

16 (40.0)

7 (30.4)

9 (52.9)

0.049

Days of MV, median (IQR) (all patients)

8.5 [6.0, 22.0]

9.0 [5.0, 23.0]

8.0 [7.0, 20.0]

0.916

Days of MV, median (IQR) (survivors)

8.5 [6.5, 20.8]

9.0 [5.0, 23.0]

8.0 [7.5, 14.0]

1.000

ICU length of stay, median (IQR)

28.0 [18.5, 56.5]

22.0 [18.0, 30.0]

39.5 [25.5, 60.0]

0.034

60-day mortality, n (%) n = 39

10 (25.6)

2 (9.1)

8 (47.1)

0.020

  1. MV mechanical ventilation, ICU intensive care unit. Data are expressed as median [IQR] or frequency (percentage)