Table 2 Risk of bias assessment of randomized controlled trials
Risk of bias | Randomization | Deviations from intended interventions | Missing outcome data | Measurement of the outcomes | Selection of the reported results | Overall risk of bias |
|---|---|---|---|---|---|---|
Kuisma et al | High | Some concerns | Some concerns | Low | Some concerns | High |
HOT or NOT | Low | High | Low | Low | Some concerns | High |
EXACT PILOT | High | High | Low | Low | Some concerns | High |
COMACARE | Low | Some concerns | Some concerns | Low | Some concerns | Some concerns |
ICU-ROX | Low | Some concerns | Some concerns | Low | Low | Some concerns |
BOX | Low | Some concerns | Low | Low | Low | Some concerns |
EXACT | Low | High | Low | Low | Low | High |
HOT-ICU | Low | Some concerns | Low | Low | Low | Some concerns |