Primary cohort (Czech Republic) | Validation cohort (Australia) | Czech Republic | |||
---|---|---|---|---|---|
Intervention n = 16 | Control n = 15 | Intervention n = 5 | Control n = 6 | Healthy Volunteers | |
Age | 58 ± 17 | 64 ± 11 | 65 ± 8.5 | 60 ± 17.8 | 64 ± 14 |
Sex (M/F) | 12/4 | 10/5 | 3/2 | 3/3 | 9/8 |
BMI | 29.2 ± 5.9 | 33.3 ± 8.1 | 26 ± 3.5 | 22 ± 2.9 | 29.9 ± 3.4 |
APACHE II | 22 ± 5 | 27 ± 7 | 21 ± 6.3 | 17 ± 4.3 | N/A |
ICU LOS pre-recruitment | 1.4 ± 0.8 | 1.4 ± 0.7 | 2 ± 0.9 | 4 ± 2.2 | N/A |
History of diabetes (%) | 6/10 (38%) | 7/8 (47%) | 0/0 (0%) | 2/6 (33%) | 0/17 (0%) |
Pre-admission CCI | 2.9 ± 2.0 | 3.7 ± 2.8 | 2 ± 1.4 | 3 ± 2.9 | N/A |
Diagnostic category | |||||
Trauma | 8 (50%) | 4(25%) | 0 (0%) | 0 (0%) | |
Surgical | 3 (19%) | 1 (7%) | 2 (40%) | 1 (16%) | |
Medical | 5 (31%) | 10 (68%) | 3 (60%) | 5 (84%) | |
Sepsis | 5 (31%) | 5 (33%) | 5 (100%) | 6 (100%) |